Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4078845..4078990 Replicon chromosome
Accession NZ_CP079645
Organism Klebsiella pneumoniae subsp. pneumoniae strain WRC24_S468MC

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4078852..4078954 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4078845..4078990 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KW559_RS20055 4074376..4075809 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
KW559_RS20060 4075925..4076164 + 240 WP_002911393.1 YebV family protein -
KW559_RS20065 4076262..4076453 + 192 WP_002911395.1 YebW family protein -
KW559_RS20070 4076450..4077103 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
KW559_RS20075 4077260..4078228 + 969 WP_004151446.1 VirK/YbjX family protein -
KW559_RS20080 4078333..4078476 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 4078845..4078990 + 146 - - Antitoxin
- 4078852..4078954 - 103 - - Toxin
KW559_RS20085 4079113..4079451 - 339 WP_002911404.1 YebY family protein -
KW559_RS20090 4079468..4080337 - 870 WP_004175431.1 copper homeostasis membrane protein CopD -
KW559_RS20095 4080341..4080715 - 375 WP_004151448.1 CopC domain-containing protein YobA -
KW559_RS20100 4080828..4081058 + 231 WP_002911406.1 DNA polymerase III subunit theta -
KW559_RS20105 4081137..4081796 + 660 WP_002911407.1 exodeoxyribonuclease X -
KW559_RS20110 4081800..4083860 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 4061448..4152281 90833


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T209624 NZ_CP079645:c4078954-4078852 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT209624 NZ_CP079645:4078845-4078990 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References