Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2017267..2017412 Replicon chromosome
Accession NZ_CP079642
Organism Klebsiella pneumoniae subsp. pneumoniae strain WRC22_AI1646MC

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2017303..2017405 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2017267..2017412 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KW558_RS09820 2012397..2014457 + 2061 WP_004151449.1 oligopeptidase B -
KW558_RS09825 2014461..2015120 - 660 WP_002911407.1 exodeoxyribonuclease X -
KW558_RS09830 2015199..2015429 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KW558_RS09835 2015542..2015916 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KW558_RS09840 2015920..2016789 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
KW558_RS09845 2016806..2017144 + 339 WP_002911404.1 YebY family protein -
- 2017267..2017412 - 146 - - Antitoxin
- 2017303..2017405 + 103 - - Toxin
KW558_RS09850 2017781..2017924 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KW558_RS09855 2018029..2018997 - 969 WP_004151446.1 VirK/YbjX family protein -
KW558_RS09860 2019154..2019807 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
KW558_RS09865 2019804..2019995 - 192 WP_002911395.1 YebW family protein -
KW558_RS09870 2020093..2020332 - 240 WP_002911393.1 YebV family protein -
KW558_RS09875 2020448..2021881 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T209603 NZ_CP079642:2017303-2017405 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT209603 NZ_CP079642:c2017412-2017267 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References