Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 235854..235999 | Replicon | plasmid pAI1527P_P1 |
| Accession | NZ_CP079635 | ||
| Organism | Klebsiella pneumoniae subsp. pneumoniae strain WRC19_AI1572C | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 235890..235992 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 235854..235999 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KW555_RS23160 (KW555_23150) | 230984..233044 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| KW555_RS23165 (KW555_23155) | 233048..233707 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| KW555_RS23170 (KW555_23160) | 233786..234016 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| KW555_RS23175 (KW555_23165) | 234129..234503 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| KW555_RS23180 (KW555_23170) | 234507..235376 | + | 870 | WP_004175431.1 | copper homeostasis membrane protein CopD | - |
| KW555_RS23185 (KW555_23175) | 235393..235731 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 235854..235999 | - | 146 | - | - | Antitoxin |
| - | 235890..235992 | + | 103 | - | - | Toxin |
| KW555_RS23190 (KW555_23180) | 236368..236511 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| KW555_RS23195 (KW555_23185) | 236616..237584 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| KW555_RS23200 (KW555_23190) | 237741..238394 | + | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| KW555_RS23205 (KW555_23195) | 238391..238582 | - | 192 | WP_002911395.1 | YebW family protein | - |
| KW555_RS23210 (KW555_23200) | 238680..238919 | - | 240 | WP_002911393.1 | YebV family protein | - |
| KW555_RS23215 (KW555_23205) | 239035..240468 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | blaSHV-28 | fyuA / ybtE / ybtT / ybtU / irp1 / irp2 / ybtA / ybtP / ybtQ / ybtX / ybtS / rcsA / kdsA / galU / sodB / mgtC / iroE | 1..1039047 | 1039047 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T209573 NZ_CP079635:235890-235992 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT209573 NZ_CP079635:c235999-235854 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
