Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2138931..2139076 Replicon chromosome
Accession NZ_CP079629
Organism Klebsiella pneumoniae subsp. pneumoniae strain WRC18_CMC307MC

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2138967..2139069 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2138931..2139076 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KW554_RS10665 2134061..2136121 + 2061 WP_004151449.1 oligopeptidase B -
KW554_RS10670 2136125..2136784 - 660 WP_043906809.1 exodeoxyribonuclease X -
KW554_RS10675 2136863..2137093 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KW554_RS10680 2137206..2137580 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KW554_RS10685 2137584..2138453 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
KW554_RS10690 2138470..2138808 + 339 WP_002911404.1 YebY family protein -
- 2138931..2139076 - 146 - - Antitoxin
- 2138967..2139069 + 103 - - Toxin
KW554_RS10695 2139445..2139588 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KW554_RS10700 2139693..2140661 - 969 WP_004151446.1 VirK/YbjX family protein -
KW554_RS10705 2140818..2141471 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
KW554_RS10710 2141468..2141659 - 192 WP_002911395.1 YebW family protein -
KW554_RS10715 2141757..2141996 - 240 WP_002911393.1 YebV family protein -
KW554_RS10720 2142112..2143545 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T209548 NZ_CP079629:2138967-2139069 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT209548 NZ_CP079629:c2139076-2138931 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References