Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2153471..2153616 Replicon chromosome
Accession NZ_CP079624
Organism Klebsiella pneumoniae subsp. pneumoniae strain WRC17_CMC307PC

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2153507..2153609 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2153471..2153616 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KW552_RS10720 2148601..2150661 + 2061 WP_004151449.1 oligopeptidase B -
KW552_RS10725 2150665..2151324 - 660 WP_043906809.1 exodeoxyribonuclease X -
KW552_RS10730 2151403..2151633 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KW552_RS10735 2151746..2152120 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KW552_RS10740 2152124..2152993 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
KW552_RS10745 2153010..2153348 + 339 WP_002911404.1 YebY family protein -
- 2153471..2153616 - 146 - - Antitoxin
- 2153507..2153609 + 103 - - Toxin
KW552_RS10750 2153985..2154128 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KW552_RS10755 2154233..2155201 - 969 WP_004151446.1 VirK/YbjX family protein -
KW552_RS10760 2155358..2156011 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
KW552_RS10765 2156008..2156199 - 192 WP_002911395.1 YebW family protein -
KW552_RS10770 2156297..2156536 - 240 WP_002911393.1 YebV family protein -
KW552_RS10775 2156652..2158085 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2080416..2171789 91373


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T209528 NZ_CP079624:2153507-2153609 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT209528 NZ_CP079624:c2153616-2153471 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References