Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 5071167..5071312 Replicon chromosome
Accession NZ_CP079606
Organism Klebsiella pneumoniae subsp. pneumoniae strain WRC15_AI1547PC

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 5071203..5071305 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 5071167..5071312 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KW550_RS24580 5066297..5068357 + 2061 WP_004151449.1 oligopeptidase B -
KW550_RS24585 5068361..5069020 - 660 WP_002911407.1 exodeoxyribonuclease X -
KW550_RS24590 5069099..5069329 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KW550_RS24595 5069442..5069816 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KW550_RS24600 5069820..5070689 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
KW550_RS24605 5070706..5071044 + 339 WP_002911404.1 YebY family protein -
- 5071167..5071312 - 146 - - Antitoxin
- 5071203..5071305 + 103 - - Toxin
KW550_RS24610 5071681..5071824 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KW550_RS24615 5071929..5072897 - 969 WP_004151446.1 VirK/YbjX family protein -
KW550_RS24620 5073054..5073707 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
KW550_RS24625 5073704..5073895 - 192 WP_002911395.1 YebW family protein -
KW550_RS24630 5073993..5074232 - 240 WP_002911393.1 YebV family protein -
KW550_RS24635 5074348..5075781 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 5000604..5078539 77935


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T209498 NZ_CP079606:5071203-5071305 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT209498 NZ_CP079606:c5071312-5071167 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References