Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1621775..1621920 Replicon chromosome
Accession NZ_CP079599
Organism Klebsiella pneumoniae subsp. pneumoniae strain WRC10_CMC309MC

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1621782..1621884 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1621775..1621920 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KWY78_RS07885 1617306..1618739 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
KWY78_RS07890 1618855..1619094 + 240 WP_002911393.1 YebV family protein -
KWY78_RS07895 1619192..1619383 + 192 WP_002911395.1 YebW family protein -
KWY78_RS07900 1619380..1620033 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
KWY78_RS07905 1620190..1621158 + 969 WP_004151446.1 VirK/YbjX family protein -
KWY78_RS07910 1621263..1621406 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 1621775..1621920 + 146 - - Antitoxin
- 1621782..1621884 - 103 - - Toxin
KWY78_RS07915 1622043..1622381 - 339 WP_002911404.1 YebY family protein -
KWY78_RS07920 1622398..1623267 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
KWY78_RS07925 1623271..1623645 - 375 WP_004151448.1 CopC domain-containing protein YobA -
KWY78_RS07930 1623758..1623988 + 231 WP_002911406.1 DNA polymerase III subunit theta -
KWY78_RS07935 1624067..1624726 + 660 WP_043906809.1 exodeoxyribonuclease X -
KWY78_RS07940 1624730..1626790 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T209473 NZ_CP079599:c1621884-1621782 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT209473 NZ_CP079599:1621775-1621920 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References