Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 651832..652391 Replicon chromosome
Accession NZ_CP079225
Organism Rhodococcus sp. LW-XY12

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KXC42_RS03150 Protein ID WP_024102981.1
Coordinates 652113..652391 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KXC42_RS03145 Protein ID WP_024102980.1
Coordinates 651832..652116 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KXC42_RS03120 (KXC42_03110) 647032..647658 + 627 WP_231913210.1 TetR/AcrR family transcriptional regulator -
KXC42_RS03125 (KXC42_03115) 647655..648083 + 429 WP_039585870.1 HIT family protein -
KXC42_RS03130 (KXC42_03120) 648088..649689 + 1602 WP_219129913.1 lactate permease LctP family transporter -
KXC42_RS03135 (KXC42_03125) 649766..650794 + 1029 WP_024102977.1 Dyp-type peroxidase -
KXC42_RS03140 (KXC42_03130) 650791..651609 + 819 WP_006551857.1 family 1 encapsulin nanocompartment shell protein -
KXC42_RS03145 (KXC42_03135) 651832..652116 + 285 WP_024102980.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
KXC42_RS03150 (KXC42_03140) 652113..652391 + 279 WP_024102981.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KXC42_RS03155 (KXC42_03145) 652448..652927 - 480 WP_006551854.1 MarR family transcriptional regulator -
KXC42_RS03160 (KXC42_03150) 652986..653738 - 753 WP_064060432.1 cutinase family protein -
KXC42_RS03165 (KXC42_03155) 653888..654550 - 663 WP_219129914.1 alpha-ketoglutarate-dependent dioxygenase AlkB -
KXC42_RS03170 (KXC42_03160) 654671..655501 + 831 WP_006551851.1 SDR family oxidoreductase -
KXC42_RS03175 (KXC42_03165) 655546..656517 + 972 WP_006551850.1 phosphotriesterase -
KXC42_RS03180 (KXC42_03170) 656554..657273 - 720 WP_033096970.1 2OG-Fe(II) oxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(34-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10268.82 Da        Isoelectric Point: 10.2002

>T209467 WP_024102981.1 NZ_CP079225:652113-652391 [Rhodococcus sp. LW-XY12]
MSTPDHPYRLVMARSAARAMARSLPEKVATAVYEFVTGPLLENPKRVGKPLNPPLAPAYSARRGEYRVLYLIDDANRTVE
VTAISHRADAYR

Download         Length: 279 bp

>T209467 NZ_CP104112:c4310274-4310167 [Escherichia coli]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10494.56 Da        Isoelectric Point: 4.2336

>AT209467 WP_024102980.1 NZ_CP079225:651832-652116 [Rhodococcus sp. LW-XY12]
MTTLPVADARAQLSRLVDEAERTHERFEITRNGHRAAVLLGADDYDAMQETIAVLSDTDLLRAHVEGRTEVESGDVVDVQ
ELTQLMRDARSSEE

Download         Length: 285 bp

>AT209467 NZ_CP104112:4310331-4310386 [Escherichia coli]
TCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References