209466

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 26380..26948 Replicon plasmid pZM32
Accession NZ_CP079224
Organism Zymomonas mobilis strain ZM401

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag KXD87_RS09740 Protein ID WP_062339523.1
Coordinates 26380..26709 (-) Length 110 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag KXD87_RS09745 Protein ID WP_062339521.1
Coordinates 26706..26948 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KXD87_RS09720 22555..22704 - 150 WP_160327978.1 hypothetical protein -
KXD87_RS09725 23989..24429 - 441 WP_062339528.1 TIR domain-containing protein -
KXD87_RS09730 24439..25881 - 1443 WP_062339526.1 SIR2 family protein -
KXD87_RS09735 26139..26306 + 168 WP_160327977.1 hypothetical protein -
KXD87_RS09740 26380..26709 - 330 WP_062339523.1 endoribonuclease MazF Toxin
KXD87_RS09745 26706..26948 - 243 WP_062339521.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
KXD87_RS09750 28941..29719 + 779 Protein_23 IS5 family transposase -
KXD87_RS09755 30130..31902 - 1773 WP_108125215.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..32791 32791


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(12-107)

Antitoxin

SpoVT-AbrB domain

(6-49)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 12159.39 Da        Isoelectric Point: 10.6796

>T209466 WP_062339523.1 NZ_CP079224:c26709-26380 [Zymomonas mobilis]
VSVKVTTVWVPVWLEFDPQAGREQAGHRPAVVLSPVSYNAKAGMMLCCPTTTKIKGYPFEVALTGKTASVVLSDQVRSLD
WRVRKTKLKDKVLPKELEAIRQRIRLLVG

Download         Length: 330 bp

>T209466 NZ_CP104112:c4309791-4309684 [Escherichia coli]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGTATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8771.04 Da        Isoelectric Point: 4.4488

>AT209466 WP_062339521.1 NZ_CP079224:c26948-26706 [Zymomonas mobilis]
MQGVVRKWGNSAAIRLPVGVLEAVGLKIDQAVDVREEDGRIIIEPVRAVPLKLEELVSGITVENRHDEMDFGSSVGCESW

Download         Length: 243 bp

>AT209466 NZ_CP104112:4309849-4309903 [Escherichia coli]
CAAGAATGGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References