Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-pasA/RelE-HTH
Location 131138..131685 Replicon chromosome
Accession NZ_CP079216
Organism Tessaracoccus palaemonis strain J1M15

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KDB89_RS00560 Protein ID WP_255556051.1
Coordinates 131422..131685 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag KDB89_RS00555 Protein ID WP_219082474.1
Coordinates 131138..131422 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KDB89_RS00540 (KDB89_00540) 126731..127810 - 1080 WP_219082470.1 histidine kinase -
KDB89_RS00545 (KDB89_00545) 127923..128642 + 720 WP_255556049.1 ABC transporter ATP-binding protein -
KDB89_RS00550 (KDB89_00550) 128639..131128 + 2490 WP_219082472.1 ABC transporter permease -
KDB89_RS00555 (KDB89_00555) 131138..131422 + 285 WP_219082474.1 ribbon-helix-helix domain-containing protein Antitoxin
KDB89_RS00560 (KDB89_00560) 131422..131685 + 264 WP_255556051.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KDB89_RS00565 (KDB89_00565) 131784..131951 - 168 WP_219082479.1 hypothetical protein -
KDB89_RS00570 (KDB89_00570) 132182..132979 - 798 WP_219082481.1 hypothetical protein -
KDB89_RS00575 (KDB89_00575) 133040..133420 + 381 WP_219082483.1 hypothetical protein -
KDB89_RS00580 (KDB89_00580) 133599..134624 - 1026 WP_219082485.1 alanine racemase -
KDB89_RS00585 (KDB89_00585) 134629..135756 - 1128 WP_219082488.1 peptidoglycan bridge formation glycyltransferase FemA/FemB family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-85)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-42)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10120.87 Da        Isoelectric Point: 10.0918

>T209462 WP_255556051.1 NZ_CP079216:131422-131685 [Tessaracoccus palaemonis]
MDWSIQTSTRFDKAIRKLDRPMARRVLVAVYALAELDEPQRRCKALTGPLAGLWRLRIGDYRVILDIRRGELVLIALDLD
HRSAIYE

Download         Length: 264 bp

>T209462 NZ_CP104112:c3784702-3784406 [Escherichia coli]
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCCCTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10357.48 Da        Isoelectric Point: 4.3568

>AT209462 WP_219082474.1 NZ_CP079216:131138-131422 [Tessaracoccus palaemonis]
MSTSVLSIRVDADIKERLDALSRATGRPAAFYVRQALLERLDDLEWAYDVARRAEAIRAGDDATAPLDALARDLGFEPDG
LKEEAHSGNLDTDR

Download         Length: 285 bp

>AT209462 NZ_CP104112:c3784404-3784009 [Escherichia coli]
ATGAAATGTCCGGTTTGCCACCAGGGAGAAATGGTTTCTGGCATTAAAGATATTCCATACACCTTCCGTGGACGAAAAAC
AGTATTGAAAGGTATCCACGGTTTATATTGTGTCCATTGCGAAGAGAGCATCATGAATAAAGAAGAGTCAGATGCTTTCA
TGGCGCAAGTAAAGGCATTTCGGGCTTCGGTGAATGCCGAAACAGTGGCACCTGAATTTATAGTGAAGGTTCGAAAAAAG
CTCTCTCTTACCCAAAAAGAGGCAAGCGAAATTTTTGGGGGAGGTGTAAATGCGTTTTCGCGTTACGAAAAAGGCAATGC
CCAACCTCATCCTTCCACAATCAAACTTTTACGTGTTCTGGATAAGCATCCAGAACTATTGAATGAAATCCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References