Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2054560..2054705 Replicon chromosome
Accession NZ_CP079179
Organism Klebsiella pneumoniae subsp. pneumoniae strain WRC13_AI2040PC

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2054596..2054698 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2054560..2054705 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KWY86_RS10005 2049690..2051750 + 2061 WP_004151449.1 oligopeptidase B -
KWY86_RS10010 2051754..2052413 - 660 WP_002911407.1 exodeoxyribonuclease X -
KWY86_RS10015 2052492..2052722 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KWY86_RS10020 2052835..2053209 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KWY86_RS10025 2053213..2054082 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
KWY86_RS10030 2054099..2054437 + 339 WP_002911404.1 YebY family protein -
- 2054560..2054705 - 146 - - Antitoxin
- 2054596..2054698 + 103 - - Toxin
KWY86_RS10035 2055074..2055217 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KWY86_RS10040 2055322..2056290 - 969 WP_004151446.1 VirK/YbjX family protein -
KWY86_RS10045 2056447..2057100 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
KWY86_RS10050 2057097..2057288 - 192 WP_002911395.1 YebW family protein -
KWY86_RS10055 2057386..2057625 - 240 WP_002911393.1 YebV family protein -
KWY86_RS10060 2057741..2059174 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1982036..2073763 91727


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T209417 NZ_CP079179:2054596-2054698 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT209417 NZ_CP079179:c2054705-2054560 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References