Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 5264490..5264635 Replicon chromosome
Accession NZ_CP079138
Organism Klebsiella pneumoniae subsp. pneumoniae strain WRC05_CMC387PC

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 5264526..5264628 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 5264490..5264635 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KWY70_RS25410 5259620..5261680 + 2061 WP_004151449.1 oligopeptidase B -
KWY70_RS25415 5261684..5262343 - 660 WP_043906809.1 exodeoxyribonuclease X -
KWY70_RS25420 5262422..5262652 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KWY70_RS25425 5262765..5263139 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KWY70_RS25430 5263143..5264012 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
KWY70_RS25435 5264029..5264367 + 339 WP_002911404.1 YebY family protein -
- 5264490..5264635 - 146 - - Antitoxin
- 5264526..5264628 + 103 - - Toxin
KWY70_RS25440 5265004..5265147 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KWY70_RS25445 5265252..5266220 - 969 WP_004151446.1 VirK/YbjX family protein -
KWY70_RS25450 5266377..5267030 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
KWY70_RS25455 5267027..5267218 - 192 WP_002911395.1 YebW family protein -
KWY70_RS25460 5267316..5267555 - 240 WP_002911393.1 YebV family protein -
KWY70_RS25465 5267671..5269104 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 5191435..5271861 80426


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T209303 NZ_CP079138:5264526-5264628 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT209303 NZ_CP079138:c5264635-5264490 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References