Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2702683..2702828 Replicon chromosome
Accession NZ_CP079131
Organism Klebsiella pneumoniae subsp. pneumoniae strain WRC04_AI1235MC

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2702719..2702821 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2702683..2702828 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KWY69_RS13185 2697813..2699873 + 2061 WP_004151449.1 oligopeptidase B -
KWY69_RS13190 2699877..2700536 - 660 WP_043906809.1 exodeoxyribonuclease X -
KWY69_RS13195 2700615..2700845 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KWY69_RS13200 2700958..2701332 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KWY69_RS13205 2701336..2702205 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
KWY69_RS13210 2702222..2702560 + 339 WP_002911404.1 YebY family protein -
- 2702683..2702828 - 146 - - Antitoxin
- 2702719..2702821 + 103 - - Toxin
KWY69_RS13215 2703197..2703340 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KWY69_RS13220 2703445..2704413 - 969 WP_004151446.1 VirK/YbjX family protein -
KWY69_RS13225 2704570..2705223 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
KWY69_RS13230 2705220..2705411 - 192 WP_002911395.1 YebW family protein -
KWY69_RS13235 2705509..2705748 - 240 WP_002911393.1 YebV family protein -
KWY69_RS13240 2705864..2707297 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2629628..2710054 80426


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T209279 NZ_CP079131:2702719-2702821 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT209279 NZ_CP079131:c2702828-2702683 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References