Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 1834086..1835608 Replicon chromosome
Accession NZ_CP079095
Organism Methylococcus sp. Mc7

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag KW115_RS09120 Protein ID WP_218808788.1
Coordinates 1834086..1835012 (-) Length 309 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag KW115_RS09125 Protein ID WP_218808789.1
Coordinates 1835009..1835608 (-) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KW115_RS09100 (KW115_09100) 1831154..1831843 + 690 WP_218808784.1 hypothetical protein -
KW115_RS09105 (KW115_09105) 1832011..1832937 + 927 WP_218808785.1 SRPBCC family protein -
KW115_RS09110 (KW115_09110) 1832983..1833369 + 387 WP_218808786.1 DUF4440 domain-containing protein -
KW115_RS09115 (KW115_09115) 1833601..1834089 - 489 WP_218808787.1 hypothetical protein -
KW115_RS09120 (KW115_09120) 1834086..1835012 - 927 WP_218808788.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
KW115_RS09125 (KW115_09125) 1835009..1835608 - 600 WP_218808789.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
KW115_RS09130 (KW115_09130) 1836559..1836783 - 225 WP_218806151.1 hypothetical protein -
KW115_RS09135 (KW115_09135) 1836780..1837538 - 759 WP_218806150.1 IS21-like element helper ATPase IstB -
KW115_RS09140 (KW115_09140) 1837528..1839057 - 1530 WP_218806149.1 IS21 family transposase -
KW115_RS09145 (KW115_09145) 1839873..1840223 - 351 WP_218808790.1 DUF2793 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(36-257)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-53)


Sequences

Toxin        


Download         Length: 309 a.a.        Molecular weight: 34278.08 Da        Isoelectric Point: 5.9769

>T209218 WP_218808788.1 NZ_CP079095:c1835012-1834086 [Methylococcus sp. Mc7]
VSSRNTAASVRARLLAKARTDKLDFNLVLTRYALERLLYRLSVSAHADHFLLKGALLFDLWFDIPHRPTRGADLLGFGSA
EIPQVEAAFRDICAVELDDGIRFQADSVHAEEIRKEANYSGVRVTLIGLLDGARCHVQVDVGFGDAVTPGPEAVDYPVML
PDMPAPRLRAYPRYTVVAEKLEALVSLGIANSRMKDYFDLWILSRYTDFDGALLCKAIHATFERRRTPLPEGVPFGLSDE
FAEDRQKQTQWQAFLRKNALVELQLSEVVAGLRAFLSLPLDALQQGAAFPQTWLAGNGWTSSSEESSR

Download         Length: 927 bp

>T209218 NZ_CP103972:c831319-831065 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAGTCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CATTGAACTTATCAAAGATACCCGCAGAACACCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAGCATAATTTGTCAG
GCTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22282.13 Da        Isoelectric Point: 10.6909

>AT209218 WP_218808789.1 NZ_CP079095:c1835608-1835009 [Methylococcus sp. Mc7]
MESQHDAILDLARAQGLLRPRDLTALGLPRVALTRLVRRGQLVRVGRGLYALPDRPVSEHASFAEVARKHPQGIVCLLSA
LRFHNLTTQSPFEVWLAIPNKARAPRMDYPPLRIVRFSGPALTEGIEAHMIDGVPVRITGVAKTVADCFKYRNKIGLDVA
LEALRDAWKGKRVGMDELWQFAKLCRVANVMRPYLESLT

Download         Length: 600 bp

>AT209218 NZ_CP103972:c831567-831316 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGCCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References