Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3445848..3445992 Replicon chromosome
Accession NZ_CP078146
Organism Klebsiella variicola strain JNQH579

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3445854..3445956 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3445848..3445992 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KW408_RS16625 (KW408_16625) 3441379..3442812 + 1434 WP_064142125.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
KW408_RS16630 (KW408_16630) 3442928..3443167 + 240 WP_002911393.1 YebV family protein -
KW408_RS16635 (KW408_16635) 3443265..3443456 + 192 WP_002911395.1 YebW family protein -
KW408_RS16640 (KW408_16640) 3443453..3444097 - 645 WP_211743849.1 protein-serine/threonine phosphatase -
KW408_RS16645 (KW408_16645) 3444254..3445222 + 969 WP_162493241.1 VirK/YbjX family protein -
KW408_RS16650 (KW408_16650) 3445326..3445469 + 144 WP_048268691.1 Ecr family regulatory small membrane protein -
- 3445848..3445992 + 145 - - Antitoxin
- 3445854..3445956 - 103 - - Toxin
KW408_RS16655 (KW408_16655) 3446114..3446452 - 339 WP_008804271.1 YebY family protein -
KW408_RS16660 (KW408_16660) 3446469..3447338 - 870 WP_117130699.1 copper homeostasis membrane protein CopD -
KW408_RS16665 (KW408_16665) 3447342..3447716 - 375 WP_008804269.1 CopC domain-containing protein YobA -
KW408_RS16670 (KW408_16670) 3447829..3448059 + 231 WP_211743848.1 DNA polymerase III subunit theta -
KW408_RS16675 (KW408_16675) 3448138..3448797 + 660 WP_008804267.1 exodeoxyribonuclease X -
KW408_RS16680 (KW408_16680) 3448801..3450861 - 2061 WP_008804266.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T209129 NZ_CP078146:c3445956-3445854 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT209129 NZ_CP078146:3445848-3445992 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References