Detailed information of TA system TA209120

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-Xre
• Location: 155526..156402
• Replicon: plasmid pNK_1
• Accession: NZ_CP078144
• Organism: Nitratireductor kimnyeongensis strain KACC 11904

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: KW403_RS18785
• Protein ID: WP_223022767.1
• Coordinates: 155890..156402 (+)
• Length: 171 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: KW403_RS18780
• Protein ID: WP_223022766.1
• Coordinates: 155526..155897 (+)
• Length: 124 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KW403_RS18765 (KW403_18765)	151512..152762	+	1251	WP_223022863.1	plasmid partitioning protein RepA	-
KW403_RS18770 (KW403_18770)	152759..153835	+	1077	WP_223022764.1	plasmid partitioning protein RepB	-
KW403_RS18775 (KW403_18775)	154065..155426	+	1362	WP_223022765.1	plasmid replication protein RepC	-
KW403_RS18780 (KW403_18780)	155526..155897	+	372	WP_223022766.1	DUF2384 domain-containing protein	Antitoxin
KW403_RS18785 (KW403_18785)	155890..156402	+	513	WP_223022767.1	RES domain-containing protein	Toxin
KW403_RS18790 (KW403_18790)	156403..156639	-	237	WP_223022864.1	WGR domain-containing protein	-
KW403_RS18795 (KW403_18795)	156725..157897	-	1173	WP_223022768.1	tyrosine-type recombinase/integrase	-
KW403_RS18800 (KW403_18800)	158020..158961	+	942	WP_223022769.1	DUF1403 family protein	-
KW403_RS18805 (KW403_18805)	159154..159762	+	609	WP_223022770.1	Ykof family thiamine-binding protein	-
KW403_RS18810 (KW403_18810)	159767..160555	+	789	WP_223022771.1	ABC transporter permease	-
KW403_RS18815 (KW403_18815)	160552..161301	+	750	WP_223022772.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..262112	262112

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (9-162)

Antitoxin

• Antitoxin Xre/MbcA/ParS-like, toxin-binding domain (71-120)

Sequences

Toxin

Protein

• Length: 171 a.a.
• Molecular weight: 18947.41 Da
• Isoelectric Point: 6.6035

>T209120 WP_223022767.1 NZ_CP078144:155890-156402 [Nitratireductor kimnyeongensis]
MPENLRTETLWRAYVPRWAHAPLSGKGAARFGGRWNPVGAEAIYAARELSTAWAEYNQGFVQHPALIAQLTLSEARLADL
TNAAVMAVHGVSTEIHQCEWRAEMDDGRVPETHRVRETLMEKGFHGVIYPSYMSPGGSCVALWQWNGEGRPVLSVTDPEH
RLPKDAASWL

Nucleotide

• Length: 513 bp

>T209120 NZ_CP103852:c1293686-1293435 [Ralstonia pseudosolanacearum]
ATGCAAAGCTGGCAGTTGCAAGCCGCCAAGGCGCGGTTTTCCGACGTCGTGAAGCGCGCTGCGGATGATGGTCCGCAGGA
AATCACGGTGCATGGCCGCCCGGTTGCGGTTGTGATCTCACGCGCACTGTTCGATCGCTTGAGTGGCAGCGGGGAGTCGC
TGGTCGACTTCATGCGCCAGTCTCCGTTGGCTGGCCTGGACGATGTCGTCTTCGAGCGCGAACGCAGCCTGCCGCGCGAG
GTCGACTTTTGA

Antitoxin

Protein

• Length: 124 a.a.
• Molecular weight: 13388.44 Da
• Isoelectric Point: 8.5234

>AT209120 WP_223022766.1 NZ_CP078144:155526-155897 [Nitratireductor kimnyeongensis]
MAATDFDFAAEHFADEKAPFLSARRVSELLGVTMVELSRLIGVARNTLTAKSGQRKVDQALSPVVRILAMATEMAGNEHR
AVIWFKHQPIPGWAGKTAYDLVGEGKADKVLTYLEAVRAGVYA

Nucleotide

• Length: 372 bp

>AT209120 NZ_CP103852:c1293438-1293025 [Ralstonia pseudosolanacearum]
TTGAGCTACCTGATCGACACCAATGTGCTGTCCGAGCTACGCCGCAAGCAGCCCGATGCGCGCGTGCTCGCCTGGATGCA
GGACCGGCCGCGCCAGTCGCTCTACCTGAGCGTGCTGACCCTGGGCGAAATCCGCAAAGGCATCGAGCGGCTGGACGACG
CAGCACGCCGCCAGCACCTGATCGACTGGCTCGAAACGGAACTGCCGAACTACTTCCTCGGCCGCTTGCTCGACGTCGAT
GCGCATACCGCCGACCGCTGGGGCCGGCTGATGTCGAGCGCCAACCGGCCGCTGCCGGCCATCGATGGCCTGCTCGCCGC
GACCGCCCTGCAGCACGACCTCATACTGGTCACGCGCAACACGAAGGATTTCGTCGGACTTGATGTCCCGCTCATCAACC
CTTGGGAAACGTGA