Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 18045..18523 Replicon plasmid pPSv_PVFi1
Accession NZ_CP078141
Organism Pseudomonas savastanoi pv. savastanoi strain PVFi1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HQ966_RS28980 Protein ID WP_002555994.1
Coordinates 18245..18523 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID H1ZX71
Locus tag HQ966_RS28975 Protein ID WP_002555995.1
Coordinates 18045..18245 (+) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HQ966_RS28950 (HQ966_28740) 13896..14642 - 747 WP_031599030.1 hypothetical protein -
HQ966_RS28955 (HQ966_28745) 15125..15553 - 429 WP_031599033.1 GntR family transcriptional regulator -
HQ966_RS28960 (HQ966_28750) 15922..16269 + 348 Protein_19 Tn3 family transposase -
HQ966_RS28965 (HQ966_28755) 16237..17454 - 1218 WP_256461770.1 MobQ family relaxase -
HQ966_RS28970 (HQ966_28760) 17473..17718 + 246 WP_002555996.1 hypothetical protein -
HQ966_RS28975 (HQ966_28765) 18045..18245 + 201 WP_002555995.1 hypothetical protein Antitoxin
HQ966_RS28980 (HQ966_28770) 18245..18523 + 279 WP_002555994.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HQ966_RS28985 (HQ966_28775) 19559..20122 + 564 WP_054082372.1 hypothetical protein -
HQ966_RS28990 (HQ966_28780) 20126..20527 + 402 WP_054082371.1 hypothetical protein -
HQ966_RS29180 20872..21006 + 135 WP_256461769.1 hypothetical protein -
HQ966_RS28995 (HQ966_28785) 20975..21541 + 567 WP_217997453.1 hypothetical protein -
HQ966_RS29000 (HQ966_28790) 21544..22860 + 1317 WP_237901258.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..41097 41097
- flank IS/Tn - - 15916..16197 281


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10732.51 Da        Isoelectric Point: 10.0464

>T209105 WP_002555994.1 NZ_CP078141:18245-18523 [Pseudomonas savastanoi pv. savastanoi]
MQIIWRQRARMSLAKIIRYISNEDPQAAQAILERLQSAILPVADHPYLYRPGRVPGTRELVAHPNYVLVYRVTLERIEVV
NVIHARQEYPSL

Download         Length: 279 bp

>T209105 NZ_CP103850:c2033526-2033350 [Staphylococcus aureus]
TTGGATAGATGGTGGCTATCTGAGTATAAGGAGGTGGTGCCTATGTTGGCATTACTGAAATCTTTAGAAAGGAGATGCCT
AATGATTACAATTAGTACCATGTTGCAGTTTGGTTTATTCCTTATTGCATTGATAGGTCTAGTAATCAAGCTTATTGAAT
TAAGCAATAAAAAATAA

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7450.22 Da        Isoelectric Point: 4.0927

>AT209105 WP_002555995.1 NZ_CP078141:18045-18245 [Pseudomonas savastanoi pv. savastanoi]
MANLSPIVSEFETDEQAASYDRWFRLQVQASLDDPSPGVPHDQVMAEMDAIIAEAEKRQQDRTKVS

Download         Length: 201 bp

>AT209105 NZ_CP103850:2033227-2033282 [Staphylococcus aureus]
AAAAAGGGCAACATGCGCAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A554FZT6

References