Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RelE(toxin) |
Location | 18045..18523 | Replicon | plasmid pPSv_PVFi1 |
Accession | NZ_CP078141 | ||
Organism | Pseudomonas savastanoi pv. savastanoi strain PVFi1 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | HQ966_RS28980 | Protein ID | WP_002555994.1 |
Coordinates | 18245..18523 (+) | Length | 93 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | H1ZX71 |
Locus tag | HQ966_RS28975 | Protein ID | WP_002555995.1 |
Coordinates | 18045..18245 (+) | Length | 67 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HQ966_RS28950 (HQ966_28740) | 13896..14642 | - | 747 | WP_031599030.1 | hypothetical protein | - |
HQ966_RS28955 (HQ966_28745) | 15125..15553 | - | 429 | WP_031599033.1 | GntR family transcriptional regulator | - |
HQ966_RS28960 (HQ966_28750) | 15922..16269 | + | 348 | Protein_19 | Tn3 family transposase | - |
HQ966_RS28965 (HQ966_28755) | 16237..17454 | - | 1218 | WP_256461770.1 | MobQ family relaxase | - |
HQ966_RS28970 (HQ966_28760) | 17473..17718 | + | 246 | WP_002555996.1 | hypothetical protein | - |
HQ966_RS28975 (HQ966_28765) | 18045..18245 | + | 201 | WP_002555995.1 | hypothetical protein | Antitoxin |
HQ966_RS28980 (HQ966_28770) | 18245..18523 | + | 279 | WP_002555994.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
HQ966_RS28985 (HQ966_28775) | 19559..20122 | + | 564 | WP_054082372.1 | hypothetical protein | - |
HQ966_RS28990 (HQ966_28780) | 20126..20527 | + | 402 | WP_054082371.1 | hypothetical protein | - |
HQ966_RS29180 | 20872..21006 | + | 135 | WP_256461769.1 | hypothetical protein | - |
HQ966_RS28995 (HQ966_28785) | 20975..21541 | + | 567 | WP_217997453.1 | hypothetical protein | - |
HQ966_RS29000 (HQ966_28790) | 21544..22860 | + | 1317 | WP_237901258.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..41097 | 41097 | |
- | flank | IS/Tn | - | - | 15916..16197 | 281 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10732.51 Da Isoelectric Point: 10.0464
>T209105 WP_002555994.1 NZ_CP078141:18245-18523 [Pseudomonas savastanoi pv. savastanoi]
MQIIWRQRARMSLAKIIRYISNEDPQAAQAILERLQSAILPVADHPYLYRPGRVPGTRELVAHPNYVLVYRVTLERIEVV
NVIHARQEYPSL
MQIIWRQRARMSLAKIIRYISNEDPQAAQAILERLQSAILPVADHPYLYRPGRVPGTRELVAHPNYVLVYRVTLERIEVV
NVIHARQEYPSL
Download Length: 279 bp
>T209105 NZ_CP103850:c2033526-2033350 [Staphylococcus aureus]
TTGGATAGATGGTGGCTATCTGAGTATAAGGAGGTGGTGCCTATGTTGGCATTACTGAAATCTTTAGAAAGGAGATGCCT
AATGATTACAATTAGTACCATGTTGCAGTTTGGTTTATTCCTTATTGCATTGATAGGTCTAGTAATCAAGCTTATTGAAT
TAAGCAATAAAAAATAA
TTGGATAGATGGTGGCTATCTGAGTATAAGGAGGTGGTGCCTATGTTGGCATTACTGAAATCTTTAGAAAGGAGATGCCT
AATGATTACAATTAGTACCATGTTGCAGTTTGGTTTATTCCTTATTGCATTGATAGGTCTAGTAATCAAGCTTATTGAAT
TAAGCAATAAAAAATAA
Antitoxin
Download Length: 67 a.a. Molecular weight: 7450.22 Da Isoelectric Point: 4.0927
>AT209105 WP_002555995.1 NZ_CP078141:18045-18245 [Pseudomonas savastanoi pv. savastanoi]
MANLSPIVSEFETDEQAASYDRWFRLQVQASLDDPSPGVPHDQVMAEMDAIIAEAEKRQQDRTKVS
MANLSPIVSEFETDEQAASYDRWFRLQVQASLDDPSPGVPHDQVMAEMDAIIAEAEKRQQDRTKVS
Download Length: 201 bp
>AT209105 NZ_CP103850:2033227-2033282 [Staphylococcus aureus]
AAAAAGGGCAACATGCGCAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG
AAAAAGGGCAACATGCGCAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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