Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/- |
| Location | 36634..37112 | Replicon | plasmid pPsv_PVFi1 |
| Accession | NZ_CP078140 | ||
| Organism | Pseudomonas savastanoi pv. savastanoi strain PVFi1 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | A0A3M5ZJX9 |
| Locus tag | HQ966_RS28620 | Protein ID | WP_044424159.1 |
| Coordinates | 36634..36927 (-) | Length | 98 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | HQ966_RS28625 | Protein ID | WP_080719061.1 |
| Coordinates | 36927..37112 (-) | Length | 62 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HQ966_RS28595 (HQ966_28390) | 31667..33340 | + | 1674 | WP_015060867.1 | radical SAM protein | - |
| HQ966_RS28600 (HQ966_28395) | 33414..33737 | + | 324 | WP_237901256.1 | NUDIX domain-containing protein | - |
| HQ966_RS28605 (HQ966_28400) | 34028..34605 | + | 578 | Protein_33 | transposase | - |
| HQ966_RS28610 (HQ966_28405) | 34657..35879 | + | 1223 | WP_095178853.1 | IS3-like element IS51 family transposase | - |
| HQ966_RS28615 (HQ966_28410) | 35967..36494 | - | 528 | WP_044320037.1 | hypothetical protein | - |
| HQ966_RS28620 (HQ966_28415) | 36634..36927 | - | 294 | WP_044424159.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| HQ966_RS28625 (HQ966_28420) | 36927..37112 | - | 186 | WP_080719061.1 | stability determinant | Antitoxin |
| HQ966_RS28630 (HQ966_28425) | 37318..37797 | - | 480 | WP_031598957.1 | DUF4411 family protein | - |
| HQ966_RS28635 (HQ966_28430) | 37784..38932 | - | 1149 | WP_031598959.1 | XRE family transcriptional regulator | - |
| HQ966_RS28640 (HQ966_28435) | 39198..39512 | - | 315 | WP_031598871.1 | HU family DNA-binding protein | - |
| HQ966_RS28645 (HQ966_28440) | 39739..41052 | - | 1314 | WP_237901247.1 | replication initiation protein | - |
| HQ966_RS28650 (HQ966_28445) | 41451..41678 | - | 228 | WP_031598867.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..72349 | 72349 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 98 a.a. Molecular weight: 11139.90 Da Isoelectric Point: 5.5666
>T209103 WP_044424159.1 NZ_CP078140:c36927-36634 [Pseudomonas savastanoi pv. savastanoi]
MLPIFWLESADNDLAAIIEYIGLCDIAAAERLWQRLRSIVLPLSEHPYLYAISDRVPGMREIVAHPNYLVFYRVTSTRIE
VVNVVHARQEYPQTGLA
MLPIFWLESADNDLAAIIEYIGLCDIAAAERLWQRLRSIVLPLSEHPYLYAISDRVPGMREIVAHPNYLVFYRVTSTRIE
VVNVVHARQEYPQTGLA
Download Length: 294 bp
>T209103 NZ_CP103850:1873935-1874030 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG
Antitoxin
Download Length: 62 a.a. Molecular weight: 7120.01 Da Isoelectric Point: 6.4675
>AT209103 WP_080719061.1 NZ_CP078140:c37112-36927 [Pseudomonas savastanoi pv. savastanoi]
MVDRSPIVSEFETEELEANYTAWLRAKVEASLADSRPAIPHDEVERRMAERLARLRHRRAS
MVDRSPIVSEFETEELEANYTAWLRAKVEASLADSRPAIPHDEVERRMAERLARLRHRRAS
Download Length: 186 bp
>AT209103 NZ_CP103850:c1874117-1874058 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|