209100

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 5892592..5893111 Replicon chromosome
Accession NZ_CP078139
Organism Pseudomonas savastanoi pv. savastanoi strain PVFi1

Toxin (Protein)


Gene name relE Uniprot ID Q48Q48
Locus tag HQ966_RS26830 Protein ID WP_002551445.1
Coordinates 5892592..5892882 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S6UWW5
Locus tag HQ966_RS26835 Protein ID WP_002551444.1
Coordinates 5892872..5893111 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HQ966_RS26815 (HQ966_26620) 5889511..5889999 - 489 WP_002551447.1 hypothetical protein -
HQ966_RS26820 (HQ966_26625) 5890175..5891434 + 1260 WP_054082596.1 IS256-like element ISPsy17 family transposase -
HQ966_RS26825 (HQ966_26630) 5891622..5892359 + 738 WP_002551446.1 hypothetical protein -
HQ966_RS26830 (HQ966_26635) 5892592..5892882 - 291 WP_002551445.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HQ966_RS26835 (HQ966_26640) 5892872..5893111 - 240 WP_002551444.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
HQ966_RS26840 (HQ966_26645) 5893275..5893748 - 474 WP_002551443.1 GNAT family N-acetyltransferase -
HQ966_RS26845 (HQ966_26650) 5893850..5894362 - 513 WP_031598429.1 GNAT family N-acetyltransferase -
HQ966_RS26850 (HQ966_26655) 5894559..5895053 + 495 WP_004667254.1 hypothetical protein -
HQ966_RS26855 (HQ966_26660) 5895087..5896361 - 1275 WP_002551441.1 OprD family porin -
HQ966_RS26860 5896576..5896809 - 234 WP_002551440.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11316.19 Da        Isoelectric Point: 10.2579

>T209100 WP_002551445.1 NZ_CP078139:c5892882-5892592 [Pseudomonas savastanoi pv. savastanoi]
MTYNLEFDARALKEWHKLGDTVRQQLKKKLATILVAPRVEANRLHALPDCYKIKLRSSGYRLVYQVIDQEVVVFVVAVDK
REREEVYRKATDRLGR

Download         Length: 291 bp

>T209100 NZ_CP103834:c1855662-1855300 [Actinobacillus genomosp. 1]
GTGAAGTTAGTTTTTGTAGAATTACCACCTTTTGAGCGATATAGACAAAAGCACCTTAGTGATGAAGAATATAGACATTT
TCAGAATGAGCTATTAGAAAATCCTAATAAAGGAGATTTAATCCAAGGTACGAACGGCTTACGCAAAATTAGAATTGCAG
ATATGCAACGAAATAAAGGTAAGAGAGGTGGAGCAAGGGTAATTTATTATCATATTGTGAATTATTCAAAAATTTTGTTG
GTTACCGCATATGGTAAAGATGAACAATCAGATTTATCTAATACGGAACGCAATATGTTAGCGAATAAAGTGAAGCGTAT
TGTTGAATTAGAGATAAGGAGTTGTAATGGGAAAACTTTTTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8955.34 Da        Isoelectric Point: 4.6017

>AT209100 WP_002551444.1 NZ_CP078139:c5893111-5892872 [Pseudomonas savastanoi pv. savastanoi]
MASINVRIDDDLKARAYLELEKLGVTPSELLRQTLQYVAERGQLPFKTVLMTEEDEALLATVRERLAAPQRVKVSLDDL

Download         Length: 240 bp

>AT209100 NZ_CP103834:c1855316-1855008 [Actinobacillus genomosp. 1]
ATGGGAAAACTTTTTGATGATTTAATGGAAGGGCTTGATGCTTATGAAAAACATATCCAAGGCAAAATCACCCTGCGAAC
CACGGTATTAGAAAAGCCTGAACCAGTAGAACTTAGCCCGTCTGAAGTTAAATCGATTCGAGAAAAATTAAATCTGTCGC
AAGCGGTTTTTGCGCATAAATTGCATACTTCCGTGCGGACTTATCAAGGGTGGGAGCAAGGCAAAACTAAACCGAATCCA
CAAGCTACTTTGTTATTACGAATGGTGGACAAATCTCCGCAATTATTAGAACAAATGGCACAGCTCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2G4DBS4

Antitoxin

Source ID Structure
AlphaFold DB A0A0K8M1G9

References