Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2012565..2012710 | Replicon | chromosome |
| Accession | NZ_CP078122 | ||
| Organism | Klebsiella pneumoniae strain KPC-2 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2012601..2012703 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2012565..2012710 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KU889_RS09880 | 2007695..2009755 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| KU889_RS09885 | 2009759..2010418 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| KU889_RS09890 | 2010497..2010727 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| KU889_RS09895 | 2010840..2011214 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| KU889_RS09900 | 2011218..2012087 | + | 870 | WP_062955019.1 | copper homeostasis membrane protein CopD | - |
| KU889_RS09905 | 2012104..2012442 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2012565..2012710 | - | 146 | - | - | Antitoxin |
| - | 2012601..2012703 | + | 103 | - | - | Toxin |
| KU889_RS09910 | 2013078..2013221 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| KU889_RS09915 | 2013326..2014294 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| KU889_RS09920 | 2014451..2015104 | + | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| KU889_RS09925 | 2015101..2015292 | - | 192 | WP_002911395.1 | YebW family protein | - |
| KU889_RS09930 | 2015390..2015629 | - | 240 | WP_002911393.1 | YebV family protein | - |
| KU889_RS09935 | 2015745..2017178 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T209042 NZ_CP078122:2012601-2012703 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT209042 NZ_CP078122:c2012710-2012565 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
