Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/YoeB-YefM |
| Location | 2821739..2822241 | Replicon | chromosome |
| Accession | NZ_CP078120 | ||
| Organism | Halomonas sp. 18071143 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | KVY02_RS13260 | Protein ID | WP_218313667.1 |
| Coordinates | 2821987..2822241 (+) | Length | 85 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A0A6H1Y4Z8 |
| Locus tag | KVY02_RS13255 | Protein ID | WP_039176654.1 |
| Coordinates | 2821739..2821990 (+) | Length | 84 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KVY02_RS13215 | 2817211..2817663 | - | 453 | WP_218313662.1 | N-acetyltransferase | - |
| KVY02_RS13220 | 2817695..2818117 | - | 423 | WP_218313663.1 | GFA family protein | - |
| KVY02_RS13225 | 2818156..2818626 | - | 471 | WP_039176635.1 | GNAT family N-acetyltransferase | - |
| KVY02_RS13230 | 2818650..2819177 | - | 528 | WP_218313664.1 | N-acetyltransferase | - |
| KVY02_RS13235 | 2819281..2819739 | - | 459 | WP_218313665.1 | OsmC family protein | - |
| KVY02_RS13240 | 2819803..2820324 | - | 522 | WP_016914639.1 | DUF2442 domain-containing protein | - |
| KVY02_RS13245 | 2820318..2820587 | - | 270 | WP_081139058.1 | DUF4160 domain-containing protein | - |
| KVY02_RS13250 | 2820754..2821575 | + | 822 | WP_218313666.1 | aldo/keto reductase | - |
| KVY02_RS13255 | 2821739..2821990 | + | 252 | WP_039176654.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin |
| KVY02_RS13260 | 2821987..2822241 | + | 255 | WP_218313667.1 | Txe/YoeB family addiction module toxin | Toxin |
| KVY02_RS13265 | 2822461..2822916 | - | 456 | WP_218313668.1 | lysophospholipase | - |
| KVY02_RS13270 | 2823023..2823304 | - | 282 | WP_218313669.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| KVY02_RS13275 | 2823301..2823573 | - | 273 | WP_016914646.1 | ribbon-helix-helix protein, CopG family | - |
| KVY02_RS13280 | 2823759..2824232 | - | 474 | WP_218313670.1 | GNAT family N-acetyltransferase | - |
| KVY02_RS13285 | 2824339..2824680 | - | 342 | WP_218315091.1 | GFA family protein | - |
| KVY02_RS13290 | 2824821..2825141 | - | 321 | WP_218313671.1 | hypothetical protein | - |
| KVY02_RS13295 | 2825204..2825893 | - | 690 | WP_218313672.1 | YafY family protein | - |
| KVY02_RS13300 | 2825990..2826388 | - | 399 | WP_218313673.1 | NUDIX domain-containing protein | - |
| KVY02_RS13305 | 2826418..2826987 | - | 570 | WP_256357494.1 | GNAT family N-acetyltransferase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 85 a.a. Molecular weight: 10220.82 Da Isoelectric Point: 9.8162
>T209033 WP_218313667.1 NZ_CP078120:2821987-2822241 [Halomonas sp. 18071143]
MKLIFSENAWEDYLYWQKTDKKILNRINKLVKEIKREPFEGVGKPEPLKHSLAGYWSRRINEEHRIVYKVTDDALLVAQL
RYHY
MKLIFSENAWEDYLYWQKTDKKILNRINKLVKEIKREPFEGVGKPEPLKHSLAGYWSRRINEEHRIVYKVTDDALLVAQL
RYHY
Download Length: 255 bp
>T209033 NZ_CP103808:2164060-2164392 [Actinobacillus genomosp. 1]
ATGAAGCGTGGCGATGTATATTGGCTTGATCTTAATCCGACATTAGGGCATGAGCAGGCTGGATGCCGTCCGGTTGTAAT
TGTATCCGCAACGGCATTTAATCTAGCGAGTAAACTGCCTGTCGTGGTACCGATTACAAACGGTGGTGCATTTGCCGAAC
GACTTGGCTTTGCGGTTTCGTTACAAAATAGCGGTTTAAAAACGACGGGAATTGTACGTTGTGACCAACCTCGTACGGTA
GATATTATTCAGCGTAACGGTAAATTTATTGAAGTATTACCTGAAGATTTACTTGATGAGGTAATGGCGAGAGTTTCCGT
TATTTTTGAGTAA
ATGAAGCGTGGCGATGTATATTGGCTTGATCTTAATCCGACATTAGGGCATGAGCAGGCTGGATGCCGTCCGGTTGTAAT
TGTATCCGCAACGGCATTTAATCTAGCGAGTAAACTGCCTGTCGTGGTACCGATTACAAACGGTGGTGCATTTGCCGAAC
GACTTGGCTTTGCGGTTTCGTTACAAAATAGCGGTTTAAAAACGACGGGAATTGTACGTTGTGACCAACCTCGTACGGTA
GATATTATTCAGCGTAACGGTAAATTTATTGAAGTATTACCTGAAGATTTACTTGATGAGGTAATGGCGAGAGTTTCCGT
TATTTTTGAGTAA
Antitoxin
Download Length: 84 a.a. Molecular weight: 9280.52 Da Isoelectric Point: 4.4750
>AT209033 WP_039176654.1 NZ_CP078120:2821739-2821990 [Halomonas sp. 18071143]
MDAISYTAARTNLAKTMEQVCEDHSPVIITRNKAQSVVMISLEDYEALQETAYLLRAPKNARRLLESVAELEQGGGQEKE
LLE
MDAISYTAARTNLAKTMEQVCEDHSPVIITRNKAQSVVMISLEDYEALQETAYLLRAPKNARRLLESVAELEQGGGQEKE
LLE
Download Length: 252 bp
>AT209033 NZ_CP103808:2163803-2164063 [Actinobacillus genomosp. 1]
ATGCCAACAGTTGCATTACGTCAAGTCGGCGGATCCGTTGCGATGGTTATTCCACCGGCTTTTCTACAAGCTCTCAATCT
TTCGGCTGGAAGTAAGGTGGATTTATCTTTGAGCGAAGAAAAGCTAGTGATAAATCCTGTTAGACCAAAAGTAAAATATA
GCCTTGAAGAATTGTTAAATCAGTCTGATTTTGAATCGGCAAGAACAGAAGAAAGTCAGATATGGTTGGATGCACCTCAA
GTTGGAAATGAGATCCTATGA
ATGCCAACAGTTGCATTACGTCAAGTCGGCGGATCCGTTGCGATGGTTATTCCACCGGCTTTTCTACAAGCTCTCAATCT
TTCGGCTGGAAGTAAGGTGGATTTATCTTTGAGCGAAGAAAAGCTAGTGATAAATCCTGTTAGACCAAAAGTAAAATATA
GCCTTGAAGAATTGTTAAATCAGTCTGATTTTGAATCGGCAAGAACAGAAGAAAGTCAGATATGGTTGGATGCACCTCAA
GTTGGAAATGAGATCCTATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|