Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 1048718..1049231 Replicon chromosome
Accession NZ_CP078120
Organism Halomonas sp. 18071143

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag KVY02_RS05035 Protein ID WP_218314605.1
Coordinates 1048965..1049231 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag KVY02_RS05030 Protein ID WP_100732319.1
Coordinates 1048718..1048972 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KVY02_RS05005 1044355..1045182 - 828 WP_016916494.1 AraC family transcriptional regulator -
KVY02_RS05010 1045358..1046110 + 753 WP_218314600.1 SDR family oxidoreductase -
KVY02_RS05015 1046144..1047037 + 894 WP_218314601.1 dihydrodipicolinate synthase family protein -
KVY02_RS05020 1047068..1048036 - 969 WP_218314603.1 putative zinc-binding metallopeptidase -
KVY02_RS05025 1048301..1048636 + 336 WP_039175928.1 zinc ribbon domain-containing protein YjdM -
KVY02_RS05030 1048718..1048972 + 255 WP_100732319.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
KVY02_RS05035 1048965..1049231 + 267 WP_218314605.1 Txe/YoeB family addiction module toxin Toxin
KVY02_RS05040 1049376..1050269 - 894 WP_062372658.1 LysR family transcriptional regulator -
KVY02_RS05045 1050415..1051626 + 1212 WP_218314606.1 YbfB/YjiJ family MFS transporter -
KVY02_RS05050 1051662..1052273 + 612 WP_081135264.1 glutathione S-transferase N-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10520.95 Da        Isoelectric Point: 9.0194

>T209027 WP_218314605.1 NZ_CP078120:1048965-1049231 [Halomonas sp. 18071143]
MSSQRLLCWTDETWNDYVYWQGQDKKTLKRINKLINDVKRSPFEGIGKPEPLKENLAGFWSRRIDDTNRLVYAVDQHAIT
VISCRYHY

Download         Length: 267 bp

>T209027 NZ_CP103807:c1853734-1853423 [Actinobacillus genomosp. 2]
GTGGGACTGCTAAAACAATCGCACAACGATAACCGTGAAAAATTGCAAAAAATCAGTCATCATTTAAGCATCTTACATTT
ACACGGTACACGAGCCGGCGAAAATTATATAAAACATTTGGAAGACCGCATTTGGCAGATTCGTCCAATGAGTGATTGTT
TATTACTTACTAGTATTATCAGAGGGCAATTTGTCTTATTGCACTATTTAGCAAAATCCCATTATCGTATCCCTAAACGG
GAAATCGAACGAGCAAAAAGCAGATTAGCAGACTTACAAGCGAGGATAAAAGATGAGCCCTATTGGTTCTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9298.46 Da        Isoelectric Point: 5.0197

>AT209027 WP_100732319.1 NZ_CP078120:1048718-1048972 [Halomonas sp. 18071143]
MKIVSFTEARNGLKAVLDGVVNDADTTVITRRDAEDAVVMSLDYYNSLMETVHLLRSPGNAEHLQRSIAQYRAGQTSARA
LMDE

Download         Length: 255 bp

>AT209027 NZ_CP103807:c1853442-1853158 [Actinobacillus genomosp. 2]
ATGAGCCCTATTGGTTCTAGTTGGCATTCATTTGAACAACAAGTGTTGAATCCTTTAGACATTGAAGAACAAAATTTCCG
CATAAAACTTATTCTTGAAATTATAGAAACCCGTCAAGCACTCGGTATTTCTCAACGCAAGTTAGAAAGTTTAAGCGGCG
TAAAGCAATCAATGATTGCCCGAGTAGAAAAAGGATCGTCCAATCCCTCTTTGGCAACACTATTAAAATTACTGGTTCCG
CTAGGTAAAACGCTACAAATCGTACCGCTGAATGCAGATAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References