Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 3898265..3898731 Replicon chromosome
Accession NZ_CP078110
Organism Cronobacter sakazakii strain MOD1-H322

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BTK77_RS18595 Protein ID WP_080321487.1
Coordinates 3898456..3898731 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag BTK77_RS18590 Protein ID WP_076727147.1
Coordinates 3898265..3898456 (+) Length 64 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BTK77_RS18570 (BTK77_018565) 3893954..3895144 - 1191 WP_007899945.1 NAD(P)/FAD-dependent oxidoreductase -
BTK77_RS18575 (BTK77_018570) 3895374..3896876 + 1503 WP_080321488.1 inorganic phosphate transporter PitA -
BTK77_RS18580 (BTK77_018575) 3896927..3897262 - 336 WP_004388311.1 universal stress protein UspB -
BTK77_RS18585 (BTK77_018580) 3897653..3898090 + 438 WP_004388310.1 universal stress protein UspA -
BTK77_RS18590 (BTK77_018585) 3898265..3898456 + 192 WP_076727147.1 stability determinant Antitoxin
BTK77_RS18595 (BTK77_018590) 3898456..3898731 + 276 WP_080321487.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BTK77_RS18600 (BTK77_018595) 3898794..3899546 - 753 WP_080321486.1 16S rRNA (guanine(1516)-N(2))-methyltransferase RsmJ -
BTK77_RS18605 (BTK77_018600) 3899555..3901597 - 2043 WP_038878963.1 oligopeptidase A -
BTK77_RS18610 (BTK77_018605) 3901791..3902633 + 843 WP_080321485.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10467.09 Da        Isoelectric Point: 5.0362

>T209007 WP_080321487.1 NZ_CP078110:3898456-3898731 [Cronobacter sakazakii]
MLPIQWTEEAKTDLFALISFVASDNPSAAQALLTRIEESILPAAYYPEMFREGRVPDTREIIAHPNYIIVYKITSEYLLV
LSVLHARQRYP

Download         Length: 276 bp

>T209007 NZ_CP103784:c1325849-1325103 [Bacillus subtilis]
ATGGTTTTATTCTTTCAGATCATGGTCTGGTGCATCGTGGCCGGACTGGGGTTATACGTGTATGCCACGTGGCGTTTCGA
AGCGAAGGTCAAAGAAAAAATGTCCGCCATCCGGAAAACTTGGTATTTGCTGTTTGTTCTGGGCGCTATGGTATACTGGA
CATATGAGCCCACTTCCCTATTTACCCACTGGGAACGGTATCTCATTGTCGCAGTCAGTTTTGCTTTGATTGATGCTTTT
ATCTTCTTAAGTGCATACGTCAAAAAACTGGCCGGCAGCGAGCTTGAAACAGACACAAGAGAAATTCTTGAAGAAAACAA
CGAAATGCTCCACATGTATCTCAATCGGCTGAAAACATACCAATACCTATTGAAAAACGAACCGATCCATGTTTATTATG
GAAGTATAGATGCTTATGCTGAAGGTATTGATAAGCTGCTGAAAACCTATGCTGATAAAATGAACTTAACGGCTTCTCTT
TGCCACTATTCGACACAGGCTGATAAAGACCGGTTAACCGAGCATATGGATGATCCGGCAGATGTACAAACACGGCTCGA
TCGAAAGGATGTTTATTACGACCAATACGGAAAAGTGGTTCTCATCCCTTTTACCATCGAGACACAGAACTATGTCATCA
AGCTGACGTCTGACAGCATTGTCACGGAATTTGATTATTTGCTATTTACGTCATTAACGAGCATATATGATTTGGTGCTG
CCAATTGAGGAGGAAGGTGAAGGATAA

Antitoxin


Download         Length: 64 a.a.        Molecular weight: 7145.21 Da        Isoelectric Point: 10.4757

>AT209007 WP_076727147.1 NZ_CP078110:3898265-3898456 [Cronobacter sakazakii]
MPKHDSPGVSSLKTHKQAEQYELWFREKVEAAAASRQPITPHDDVMASARKIIESAKVRRKMA

Download         Length: 192 bp

>AT209007 NZ_CP103784:c1325103-1324933 [Bacillus subtilis]
ATGGAACGTGCGTTTCAAAACAGATGCGAGCCCAGAGCGGCGAAGCCGTTTAAAATCCTGAAAAAACGTTCAACCACCAG
TGTCGCAAGCTATCAAGTCAGTCCGCATACAGCAAGAATCTTCAAAGAAAACGAACGGCTGATTGACGAGTATAAACGAA
AAAAAGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References