Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 457022..457633 Replicon chromosome
Accession NZ_CP078069
Organism Comamonas sp. NLF-1-9

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KUD94_RS02175 Protein ID WP_218238278.1
Coordinates 457337..457633 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KUD94_RS02170 Protein ID WP_218238277.1
Coordinates 457022..457333 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KUD94_RS02150 (KUD94_02150) 452631..454577 - 1947 WP_218238273.1 lamin tail domain-containing protein -
KUD94_RS02155 (KUD94_02155) 454874..455248 - 375 WP_218238274.1 hypothetical protein -
KUD94_RS02160 (KUD94_02160) 455328..455876 - 549 WP_218238275.1 hypothetical protein -
KUD94_RS02165 (KUD94_02165) 455873..456889 - 1017 WP_218238276.1 hypothetical protein -
KUD94_RS02170 (KUD94_02170) 457022..457333 - 312 WP_218238277.1 putative addiction module antidote protein Antitoxin
KUD94_RS02175 (KUD94_02175) 457337..457633 - 297 WP_218238278.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KUD94_RS02185 (KUD94_02185) 457991..458197 - 207 WP_218238280.1 type II toxin-antitoxin system HicB family antitoxin -
KUD94_RS02190 (KUD94_02190) 458560..458799 - 240 WP_218238281.1 DUF1010 domain-containing protein -
KUD94_RS02195 (KUD94_02195) 459228..460253 + 1026 WP_218238282.1 integron integrase -
KUD94_RS02200 (KUD94_02200) 460275..462011 - 1737 WP_218238283.1 thiosulfohydrolase SoxB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Uncharacterized protein HI1420

(12-98)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11003.60 Da        Isoelectric Point: 8.5282

>T208960 WP_218238278.1 NZ_CP078069:c457633-457337 [Comamonas sp. NLF-1-9]
MYTIQRTEQFSGWLDGLKDRVARGRLVRRLEKAQRGLLGDVQHVGEGVFEMREFFGPGWRMYYVQRGAVLIVMLGGGDKS
TQQADIAAAQTLAATLEE

Download         Length: 297 bp

>T208960 NZ_CP103762:c3934142-3933222 [Escherichia coli]
ATGGATCTGCGTGATAGCTATGCCCGGCAGGTCAAACTGTTGATGGCCGCTCTGCCGTATGTGGCGAAGGAGTCCTGTTT
CGCGTTGAAAGGCGGCACCGCAATCAATTTGTTTGTGCAGGATTTTCCCCGTCTGTCGGTGGATATTGATCTGGCGTATA
AGAGCTTTGCGGATCGCGATACTGATCTGGCGGCTATCAACGACGCTTTGAAGAGGATTACTGCATCGCTGAACGGCAGA
CCGGGGATCACCGCGATTCGGCAGGAAAATAAAGCGGATGAAAAGCGCATCATTGTGAATACCGCTGATGCAAAGATTAA
GATCGAGGTTAGCCCGGTCTGGCGCGGGCTGTTGTTGCCTCCGGCAGAAATGCCTGTGTGCGAACGTGTGGAAATGGAGT
ATGGCTTCACCACCATGAGTGTCGTCTCGCTGGCGGATCTTTATGGCGGTAAAATCTGCGCAGCGCTTGATCGTCAGCAC
CCGCGCGATCTGTTTGATGTGCTGAATATGCTGGAGAAACCGGGACTGATGCGGGAGATCTTTGACGGTTTTCTTTGTTA
TCTGGCAGGCCATCCCCGCCCCATTGCCGAGTTGCTGGCCCCAAACTGGGATACAGAGCGGATCACGACGCTGTATGCTC
AGGAATTTTCGGGGATGACTCAGCAGGAAACGTCGCTGGAATCGCTGCTGTCAGTAACGACTTTGCTGCCGCAGGCGTTG
AAGTCACATCTTACGGATCTGGATCGCGAGTTCTTGCTCAGTTTTAAGCAAAACAGCCCTGACTGGTCGCGGTATCGCTA
TCCTGAAATTCAGCATCTTCCGGCTATTCGCTGGAAGCAACGTAATCTGGCGGTGCTGAAAGATAAAAATCCGGCGAAGT
ATGTGGCGGCGGTGAATAAGCTAGAGAGGGTGCTGGCGTAA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11110.85 Da        Isoelectric Point: 7.9971

>AT208960 WP_218238277.1 NZ_CP078069:c457333-457022 [Comamonas sp. NLF-1-9]
MKKPEKIKISDLPVFDAAEYLKSEEDIAIYLTLAIEENDPAGLADALGTIARARGMTEVARASGLTREALYKALRPGSHP
RFDTIARVCGALGVKLVAQPSRT

Download         Length: 312 bp

>AT208960 NZ_CP103762:c3934911-3934129 [Escherichia coli]
TTGCCAAACTATCTAAACTGGCTGATGCAGCACACGCTACCCGGCCAGGTGCTGCTCCAGTCATGGCTTACCCGCAACGG
CATAGATCGTAAGCTCTCTTATCTCTATGTGAAGAATGGCTGGCTCAGGCGGATCGCTCACGGCGTATACTGCCGGACGG
GTCGTGAACCGGATTGGGTGGATGCGGTTTACTGCCTGCAATCGCAGTGGGAAAAGCCTGTTCGGGTGGCGGGGCTAACC
AGCCTTGCGCTTCAGGGTCATGCGCACTATACCGAACAGGGTAAGCCGCAGGTCTGGCTCGCGCTTCCGGCTTACGTCAA
ACTGCCGGGATGGTTTTCTGCCTTTGAACAATCCGCAACATTTGTCACGCTGTATACGTCAGGCCTTACCGCTGATGTAA
CGCCATTTACTACGGAACTGAAAATTGGTGACCGGCAGTTAGCGGGCAGTGTCCCGGAACTGGTCGCGTATGAGATCGCT
TGTGGCGTTCCTTCGTTGATCTCGTTCGAACATGCCGATGCTCTGTTTCAGGGGATGAATCTTCTCAGCCCGCGTAAATT
GCAGGCGTTACTCTGCGCCAGTCATTCGGTTAAAACCAACCGGGTGATGCTTTACCTTGCCCGGCGTAATGGACACCCTT
ATTTTCAGTTTATTGATCAAAGCGGTATAGAAACAGGTACGGGAAAGCGGCAAATCATACCCGGCGGCTGGCTGGAGCCG
GATTATCAAATTACTGTTCCACGCGCATTTAAACCGGAAGGAGTCGAAGATGGATCTGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References