Detailed information of TA system TA208950

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-YefM
• Location: 4452651..4453201
• Replicon: chromosome
• Accession: NZ_CP078038
• Organism: Shewanella putrefaciens strain SA70

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: B7D78_RS19560
• Protein ID: WP_086903216.1
• Coordinates: 4452902..4453201 (+)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: B7D78_RS19555
• Protein ID: WP_086903215.1
• Coordinates: 4452651..4452893 (+)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
B7D78_RS19530 (KVP08_019530)	4447830..4449053	+	1224	WP_086903210.1	beta-ketoacyl-[acyl-carrier-protein] synthase family protein	-
B7D78_RS19535 (KVP08_019535)	4449059..4449598	+	540	WP_086903211.1	hotdog family protein	-
B7D78_RS19540 (KVP08_019540)	4449724..4450449	+	726	WP_086903212.1	3-ketoacyl-ACP reductase FabG2	-
B7D78_RS19545 (KVP08_019545)	4450450..4451703	+	1254	WP_086903213.1	beta-ketoacyl-ACP synthase	-
B7D78_RS19550 (KVP08_019550)	4451714..4452457	+	744	WP_086903214.1	hypothetical protein	-
B7D78_RS19555 (KVP08_019555)	4452651..4452893	+	243	WP_086903215.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
B7D78_RS19560 (KVP08_019560)	4452902..4453201	+	300	WP_086903216.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-90)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-64)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11529.32 Da
• Isoelectric Point: 10.0230

>T208950 WP_086903216.1 NZ_CP078038:4452902-4453201 [Shewanella putrefaciens]
MNNKRYKLSRLAQAHLLKIKDYTLQHFSESQWHKYKQSLISGLQMLANHPGLGRSCNDIYPNGFYFPIGKHTAYFTKEDD
FILIVALLGQPQLPQNHLK

Nucleotide

• Length: 300 bp

>T208950 NZ_CP103762:1944132-1944383 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 8982.23 Da
• Isoelectric Point: 5.0621

>AT208950 WP_086903215.1 NZ_CP078038:4452651-4452893 [Shewanella putrefaciens]
MQTLTANDAKRNFGELLLNAQREPIKISKNSKDVVVVMSIHDYEQLEAMKADYLKHCFNAAKEDLAKGNVVDGEDFLNAL

Nucleotide

• Length: 243 bp

>AT208950 NZ_CP103762:1944380-1944634 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA