Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | VII | Classification (family/domain) | HepT-MntA/HepT(toxin) |
Location | 3234222..3235038 | Replicon | chromosome |
Accession | NZ_CP078038 | ||
Organism | Shewanella putrefaciens strain SA70 |
Toxin (Protein)
Gene name | hepT | Uniprot ID | A0A252EQR5 |
Locus tag | B7D78_RS14150 | Protein ID | WP_069455295.1 |
Coordinates | 3234637..3235038 (+) | Length | 134 a.a. |
Antitoxin (Protein)
Gene name | mntA | Uniprot ID | A0A501X4H4 |
Locus tag | B7D78_RS14145 | Protein ID | WP_069455294.1 |
Coordinates | 3234222..3234644 (+) | Length | 141 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
B7D78_RS14125 (KVP08_014125) | 3229636..3230526 | - | 891 | WP_086904476.1 | glucose-1-phosphate thymidylyltransferase RfbA | - |
B7D78_RS14130 (KVP08_014130) | 3230850..3232211 | - | 1362 | WP_086904477.1 | GAF domain-containing sensor histidine kinase | - |
B7D78_RS14135 (KVP08_014135) | 3232629..3233072 | + | 444 | WP_086904478.1 | copper resistance protein NlpE | - |
B7D78_RS14140 (KVP08_014140) | 3233348..3234115 | + | 768 | WP_086904479.1 | HutD family protein | - |
B7D78_RS14145 (KVP08_014145) | 3234222..3234644 | + | 423 | WP_069455294.1 | type II toxin-antitoxin system antitoxin | Antitoxin |
B7D78_RS14150 (KVP08_014150) | 3234637..3235038 | + | 402 | WP_069455295.1 | type II toxin-antitoxin system toxin | Toxin |
B7D78_RS14155 (KVP08_014155) | 3235232..3236263 | - | 1032 | WP_218558454.1 | dTDP-glucose 4,6-dehydratase | - |
B7D78_RS14160 (KVP08_014160) | 3236821..3238382 | + | 1562 | Protein_2745 | IS3 family transposase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 134 a.a. Molecular weight: 15296.57 Da Isoelectric Point: 6.3185
>T208948 WP_069455295.1 NZ_CP078038:3234637-3235038 [Shewanella putrefaciens]
MNDIIINKIATIKRCIKRIQQVYGDGSQFKQDFTLQDSVILNLQRCCEACIDIANHINRQQQLGIPQSSRDSFTLLAQNN
LITQPLADNLKKMVGLRNIAVHDYQELNLDIVVHVVQHHLEDFEQFIDVIKAE
MNDIIINKIATIKRCIKRIQQVYGDGSQFKQDFTLQDSVILNLQRCCEACIDIANHINRQQQLGIPQSSRDSFTLLAQNN
LITQPLADNLKKMVGLRNIAVHDYQELNLDIVVHVVQHHLEDFEQFIDVIKAE
Download Length: 402 bp
>T208948 NZ_CP103762:1026661-1026996 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCCGG
ACATCGTCCGGCTGTTGTCCTGAGTCCGTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACGGTTGCCCCAGAGGAATTACAGCTCATTAAAGCCAAAATTAA
CGTGCTGATTGGGTAG
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCCGG
ACATCGTCCGGCTGTTGTCCTGAGTCCGTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACGGTTGCCCCAGAGGAATTACAGCTCATTAAAGCCAAAATTAA
CGTGCTGATTGGGTAG
Antitoxin
Download Length: 141 a.a. Molecular weight: 15795.88 Da Isoelectric Point: 5.1520
>AT208948 WP_069455294.1 NZ_CP078038:3234222-3234644 [Shewanella putrefaciens]
MQQLNEKKIIKLLRDNIPKLQLIYLFGSYSQGTQHRNSDIDIAVLAADTLDNIARWELAQKLASALDSDVDLVDLRSAST
VLCQQVVTQGKQLWGTQQDDELFAVKTISMYQHLQAERQAIIDDVMANTAAKDHRGSHFE
MQQLNEKKIIKLLRDNIPKLQLIYLFGSYSQGTQHRNSDIDIAVLAADTLDNIARWELAQKLASALDSDVDLVDLRSAST
VLCQQVVTQGKQLWGTQQDDELFAVKTISMYQHLQAERQAIIDDVMANTAAKDHRGSHFE
Download Length: 423 bp
>AT208948 NZ_CP103762:1026413-1026661 [Escherichia coli]
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A252EQR5 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A501X4H4 |