Detailed information of TA system TA208947

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ParE-CopA/RHH(antitoxin)
• Location: 2704301..2704866
• Replicon: chromosome
• Accession: NZ_CP078038
• Organism: Shewanella putrefaciens strain SA70

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: B7D78_RS11865
• Protein ID: WP_086904862.1
• Coordinates: 2704573..2704866 (+)
• Length: 98 a.a.

Antitoxin (Protein)

• Gene name: copA
• Uniprot ID: A0A8F5K304
• Locus tag: B7D78_RS11860
• Protein ID: WP_047539044.1
• Coordinates: 2704301..2704585 (+)
• Length: 95 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
B7D78_RS11825 (KVP08_011825)	2700140..2700349	-	210	WP_176370378.1	AlpA family transcriptional regulator	-
B7D78_RS11830 (KVP08_011830)	2700484..2700990	+	507	WP_176370377.1	DNA repair protein RadC	-
B7D78_RS11835 (KVP08_011835)	2701031..2701393	+	363	WP_086904857.1	hypothetical protein	-
B7D78_RS11840 (KVP08_011840)	2701524..2701898	+	375	WP_086904858.1	type IV toxin-antitoxin system YeeU family antitoxin	-
B7D78_RS11845 (KVP08_011845)	2702116..2702529	+	414	WP_086904859.1	DUF2787 domain-containing protein	-
B7D78_RS11850 (KVP08_011850)	2702638..2703204	+	567	WP_086904860.1	site-specific integrase	-
B7D78_RS11855 (KVP08_011855)	2703292..2704014	+	723	WP_086904861.1	lecithin retinol acyltransferase family protein	-
B7D78_RS11860 (KVP08_011860)	2704301..2704585	+	285	WP_047539044.1	CopG family ribbon-helix-helix protein	Antitoxin
B7D78_RS11865 (KVP08_011865)	2704573..2704866	+	294	WP_086904862.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
B7D78_RS11870 (KVP08_011870)	2704891..2706500	-	1610	Protein_2313	IS1634 family transposase	-
B7D78_RS11875 (KVP08_011875)	2706737..2707414	-	678	WP_086904680.1	inovirus Gp2 family protein	-
B7D78_RS11880 (KVP08_011880)	2707730..2709199	-	1470	WP_086904679.1	YfjI family protein	-
B7D78_RS11885 (KVP08_011885)	2709237..2709449	-	213	WP_080612395.1	AlpA family phage regulatory protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-95)

Antitoxin

• Ribbon-helix-helix protein, CopG (7-44)

Sequences

Toxin

Protein

• Length: 98 a.a.
• Molecular weight: 11139.72 Da
• Isoelectric Point: 6.9779

>T208947 WP_086904862.1 NZ_CP078038:2704573-2704866 [Shewanella putrefaciens]
MPQIVFTATALRDLERLREFLRSKKPPAAQRAASAIINTIRKLESYPDIGRPIDDNDFSFRELLIDFGDTGYLAMYQYDG
GERLTVLCIRHQKEAGY

Nucleotide

• Length: 294 bp

>T208947 NZ_CP103762:931208-931621 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCGCAGTGGCTTTCCTTGCTGCTTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCGCTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGCATTAATGCTCGCCAGGGGGAAATTCGCCTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCGCCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATAGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATCAAGATGA

Antitoxin

Protein

• Length: 95 a.a.
• Molecular weight: 10982.32 Da
• Isoelectric Point: 6.3342

>AT208947 WP_047539044.1 NZ_CP078038:2704301-2704585 [Shewanella putrefaciens]
MSTIKPVSVKLDADIKARVEHLAETRKRSSHWMMREAIREYVEREEKREALQQEALRAWEEHQTSGLHVTGDEVVNWLES
WGSENEKAAPTCHK

Nucleotide

• Length: 285 bp

>AT208947 NZ_CP103762:930961-931227 [Escherichia coli]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTATGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCAGACC
TGTTCAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAATTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA