Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2038386..2038531 Replicon chromosome
Accession NZ_CP078033
Organism Klebsiella pneumoniae strain KP_160

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2038422..2038524 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2038386..2038531 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EGK18_RS09900 2033516..2035576 + 2061 WP_004151449.1 oligopeptidase B -
EGK18_RS09905 2035580..2036239 - 660 WP_043906809.1 exodeoxyribonuclease X -
EGK18_RS09910 2036318..2036548 - 231 WP_002911406.1 DNA polymerase III subunit theta -
EGK18_RS09915 2036661..2037035 + 375 WP_004151448.1 CopC domain-containing protein YobA -
EGK18_RS09920 2037039..2037908 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
EGK18_RS09925 2037925..2038263 + 339 WP_002911404.1 YebY family protein -
- 2038386..2038531 - 146 - - Antitoxin
- 2038422..2038524 + 103 - - Toxin
EGK18_RS09930 2038900..2039043 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
EGK18_RS09935 2039148..2040116 - 969 WP_004151446.1 VirK/YbjX family protein -
EGK18_RS09940 2040273..2040926 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
EGK18_RS09945 2040923..2041114 - 192 WP_002911395.1 YebW family protein -
EGK18_RS09950 2041212..2041451 - 240 WP_002911393.1 YebV family protein -
EGK18_RS09955 2041567..2043000 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T208924 NZ_CP078033:2038422-2038524 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT208924 NZ_CP078033:c2038531-2038386 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References