Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 10284..10821 Replicon plasmid pAV_175-3
Accession NZ_CP078029
Organism Acinetobacter variabilis strain AV_175

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EGK58_RS16560 Protein ID WP_005265046.1
Coordinates 10284..10574 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag EGK58_RS16565 Protein ID WP_125279911.1
Coordinates 10561..10821 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EGK58_RS16540 (EGK58_016540) 5308..6057 - 750 WP_125279806.1 molecular chaperone -
EGK58_RS16545 (EGK58_016545) 6082..6552 - 471 WP_125279807.1 spore coat U domain-containing protein -
EGK58_RS16550 (EGK58_016550) 7845..8372 - 528 WP_125279808.1 plasmid pRiA4b ORF-3 family protein -
EGK58_RS16555 (EGK58_016555) 8587..9198 + 612 WP_004641910.1 recombinase family protein -
EGK58_RS16560 (EGK58_016560) 10284..10574 - 291 WP_005265046.1 type II toxin-antitoxin system YafQ family toxin Toxin
EGK58_RS16565 (EGK58_016565) 10561..10821 - 261 WP_125279911.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
EGK58_RS16575 (EGK58_016575) 12693..12899 - 207 WP_110989417.1 hypothetical protein -
EGK58_RS16580 (EGK58_016580) 13809..14342 - 534 WP_125279826.1 plasmid replication DNA-binding protein -
EGK58_RS16585 (EGK58_016585) 14410..15366 - 957 WP_171431295.1 replication initiation protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..19844 19844


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-94)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-69)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11213.96 Da        Isoelectric Point: 8.8769

>T208917 WP_005265046.1 NZ_CP078029:c10574-10284 [Acinetobacter variabilis]
MRTIKYTSAFKKDYKREKKGQHRNTVDAELQTVLELLQADETLPEKYRDHALVSNWVGHRDCHIKPDLVLIYKKTEEGEL
LILKLVRLGSHSELAI

Download         Length: 291 bp

>T208917 NZ_CP103756:c175582-175166 [Escherichia coli]
GTGAACAAGATCTATATGCTCGACACGAACATCTGCTCGTTCATCATGCGCGAGCAACCTGAAGCATTGCTTAAGCACCT
GGAGCAGTCGGTGCTGCGCGGTCACCGTATCGTGGTCTCGGCCATCACCTACTCCGAGATGCGCTTCGGTGCCACCGGTC
CGAAGGCCTCGCCACGCCACGTGCAACTGGTTGACGCGTTCTGTGAGAGGCTCGATGCCGTCCTGCCGTGGGACCGCGCC
GCGGTGGATGCGACCACGGAGATTAAGGTGGCACTGCGTCTCGCCGGCACGCCGATCGGTCCGAACGACACGGCGATAGC
CGGACACGCCATCGCTGCCTGTGCCATTCTGGTGACGAATAATGTGAGAGAGTTTGAGCGGGTACCGGGTCTTGTGCTGG
AAGACTGGGTAAGATAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9379.73 Da        Isoelectric Point: 4.4354

>AT208917 WP_125279911.1 NZ_CP078029:c10821-10561 [Acinetobacter variabilis]
MASNSLVTTRINENIKHEATEVLATMGLTVSDAVRLLLTKVAKEKALPFEIWQPSAETIAAMEEDLSKAKSFTSVKDLMA
DLNADD

Download         Length: 261 bp

>AT208917 NZ_CP103756:c175809-175579 [Escherichia coli]
ATGAGAACCGTATCCATTTTTAAAAATGGCAACAACCGTGCTATCCGCCTTCCACGCGATCTGGATTTTGAGGGGGTGAG
CGAGCTGGAGATCGTCCGGGAAGGGGACAGCATCATTCTGCGCCCCGTCCGGCCGACCTGGGGCTCATTCCTGGAGCTAG
AAAAGGCCGATCCGGACTTTATGACGGAGCGCGAGGACGTTGTCAGCGACGAAGGACGAGTTAACCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References