Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 557337..557973 Replicon chromosome
Accession NZ_CP078027
Organism Acinetobacter variabilis strain AV_175

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag EGK58_RS02580 Protein ID WP_125278961.1
Coordinates 557587..557973 (+) Length 129 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag EGK58_RS02575 Protein ID WP_125278962.1
Coordinates 557337..557594 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EGK58_RS02555 (EGK58_002555) 552838..553845 + 1008 WP_004786889.1 DNA-directed RNA polymerase subunit alpha -
EGK58_RS02560 (EGK58_002560) 553864..554229 + 366 WP_004786886.1 50S ribosomal protein L17 -
EGK58_RS02565 (EGK58_002565) 554438..555928 + 1491 WP_125278964.1 NAD(P)/FAD-dependent oxidoreductase -
EGK58_RS02570 (EGK58_002570) 555982..557154 - 1173 WP_125278963.1 acyl-CoA dehydrogenase family protein -
EGK58_RS02575 (EGK58_002575) 557337..557594 + 258 WP_125278962.1 succinate dehydrogenase assembly factor 2 Antitoxin
EGK58_RS02580 (EGK58_002580) 557587..557973 + 387 WP_125278961.1 hypothetical protein Toxin
EGK58_RS02585 (EGK58_002585) 558520..559560 + 1041 WP_125278960.1 hypothetical protein -
EGK58_RS02590 (EGK58_002590) 559633..560205 + 573 WP_125278959.1 rhombosortase -
EGK58_RS02595 (EGK58_002595) 560383..562665 + 2283 WP_125278958.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-80)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 15246.42 Da        Isoelectric Point: 10.0581

>T208914 WP_125278961.1 NZ_CP078027:557587-557973 [Acinetobacter variabilis]
MDNRCFRLKRSKCALVFQLFIFAVLMFLLYQLLPVIMWLVCGVIGLVIYQLFYRKIPHIEQFEYLDGREWSLTAAAQGTR
RVLISHVIDHQAYIVVYFQHAKARPLLIWCDQLPFKQWKSLKVLTKIL

Download         Length: 387 bp

>T208914 NZ_CP103755:c4769116-4768943 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTTCTGGTCGGAATAACCTGGCCAATGAGTTTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10309.80 Da        Isoelectric Point: 4.4709

>AT208914 WP_125278962.1 NZ_CP078027:557337-557594 [Acinetobacter variabilis]
MTDDITLEERKVIYRARRGLKEIDVYFDPYVKNYYLNADPFEKEMFAELVAQEDPDLLDWFMEVSEPPRPELKDFIKKLK
FYVHG

Download         Length: 258 bp

>AT208914 NZ_CP103755:c4769440-4769144 [Escherichia coli]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGGTT
AAGATCATTGATGTATGATATGAATTTCTCCTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAACT
CCTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTCAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAGCATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References