Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 2491945..2492556 Replicon chromosome
Accession NC_004556
Organism Xylella fastidiosa Temecula1

Toxin (Protein)


Gene name relE Uniprot ID Q879T9
Locus tag PD_RS11120 Protein ID WP_011098375.1
Coordinates 2492257..2492556 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q879U0
Locus tag PD_RS11115 Protein ID WP_004085003.1
Coordinates 2491945..2492253 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PD_RS11085 2488515..2489276 - 762 WP_004090267.1 Bax inhibitor-1/YccA family protein -
PD_RS11110 2490468..2491871 + 1404 WP_011098374.1 hypothetical protein -
PD_RS11115 2491945..2492253 - 309 WP_004085003.1 putative addiction module antidote protein Antitoxin
PD_RS11120 2492257..2492556 - 300 WP_011098375.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PD_RS11125 2492644..2493189 + 546 WP_011098376.1 hypothetical protein -
PD_RS12865 2493201..2493344 + 144 WP_155115087.1 hypothetical protein -
PD_RS11130 2493497..2493877 - 381 WP_004089371.1 DUF596 domain-containing protein -
PD_RS11135 2493882..2495012 - 1131 WP_011098377.1 DUF769 domain-containing protein -
PD_RS11140 2495320..2495700 - 381 WP_004087391.1 DUF596 domain-containing protein -
PD_RS11145 2495712..2497286 - 1575 Protein_2157 DUF637 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2442712..2493006 50294


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-98)

Antitoxin

Uncharacterized protein HI1420

(15-100)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11378.17 Da        Isoelectric Point: 10.3861

>T20876 WP_011098375.1 NC_004556:c2492556-2492257 [Xylella fastidiosa Temecula1]
MTYTLKRLEGFSDWLKGLKDGLARQRLIKRLRKVQLGNFGDVQPVGEGVFEMREHFGPGWRMYYVQRGSFLIVMLGGGDK
STQQSDIRRAIELAKSLED

Download         Length: 300 bp

>T20876 NC_004556:c2492556-2492257 [Xylella fastidiosa Temecula1]
ATGACCTACACGCTAAAACGACTTGAAGGGTTCTCTGACTGGCTAAAGGGCCTAAAGGATGGGCTGGCAAGGCAGCGCCT
CATCAAGCGCTTACGCAAGGTGCAGCTCGGCAACTTTGGAGACGTGCAGCCGGTGGGTGAAGGCGTGTTTGAAATGCGCG
AACACTTCGGACCTGGCTGGCGTATGTACTACGTGCAGCGAGGCAGCTTTCTCATCGTGATGCTCGGCGGCGGCGACAAG
TCAACGCAGCAATCAGACATTCGTCGGGCCATTGAGCTAGCAAAATCTTTAGAGGATTGA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11060.61 Da        Isoelectric Point: 4.6535

>AT20876 WP_004085003.1 NC_004556:c2492253-2491945 [Xylella fastidiosa Temecula1]
VTITKKINVSELPEFDAAEYLNSEEEVAAYLTAVLEENDPALLAAALGDIARSRGMSQIAKDSGITREALYKALRPGSEP
RFDTISRVCTALGIRLVAQPMH

Download         Length: 309 bp

>AT20876 NC_004556:c2492253-2491945 [Xylella fastidiosa Temecula1]
GTGACCATCACAAAGAAAATCAATGTCTCCGAACTGCCAGAGTTCGATGCCGCCGAATACCTGAACAGCGAAGAGGAGGT
AGCCGCGTATCTCACGGCTGTTCTTGAAGAAAACGATCCAGCACTGTTAGCGGCTGCGCTTGGTGACATTGCCCGTTCAC
GTGGTATGTCTCAGATTGCGAAGGATTCTGGCATCACGCGGGAAGCTCTATACAAGGCCCTTCGGCCTGGTAGTGAACCA
CGCTTCGATACGATAAGCCGCGTCTGTACCGCCCTAGGTATACGTCTAGTAGCGCAACCAATGCATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q879T9

Antitoxin

Source ID Structure
AlphaFold DB A0A060HCD4

References