Detailed information of TA system TA020873

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-dinJ/YafQ-RelB
• Location: 1298233..1298764
• Replicon: chromosome
• Accession: NC_004556
• Organism: Xylella fastidiosa Temecula1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: Q87CH1
• Locus tag: PD_RS05775
• Protein ID: WP_004090909.1
• Coordinates: 1298483..1298764 (+)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: dinJ
• Uniprot ID: Q87CH2
• Locus tag: PD_RS05770
• Protein ID: WP_004090907.1
• Coordinates: 1298233..1298496 (+)
• Length: 88 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PD_RS05745	1293459..1294637	-	1179	WP_011097931.1	phage tail sheath family protein	-
PD_RS05750	1294702..1296294	-	1593	WP_011097932.1	tail fiber domain-containing protein	-
PD_RS05755	1296302..1296859	-	558	WP_011097610.1	phage tail protein I	-
PD_RS05760	1296852..1297745	-	894	WP_011097611.1	baseplate J/gp47 family protein	-
PD_RS05765	1297745..1298083	-	339	WP_004090694.1	GPW/gp25 family protein	-
PD_RS05770	1298233..1298496	+	264	WP_004090907.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
PD_RS05775	1298483..1298764	+	282	WP_004090909.1	type II toxin-antitoxin system YafQ family toxin	Toxin
PD_RS05780	1298801..1299388	-	588	WP_011097612.1	phage baseplate assembly protein V	-
PD_RS05785	1299385..1299927	-	543	WP_011097613.1	hypothetical protein	-
PD_RS05790	1299903..1300424	-	522	WP_011097614.1	hypothetical protein	-
PD_RS05795	1300421..1300744	-	324	WP_011097935.1	hypothetical protein	-
PD_RS05800	1300744..1301004	-	261	WP_011097616.1	hypothetical protein	-
PD_RS05805	1301022..1302896	-	1875	WP_011097936.1	phage major capsid protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1284820..1331541	46721

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-91)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (4-70)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10936.37 Da
• Isoelectric Point: 7.2205

>T20873 WP_004090909.1 NC_004556:1298483-1298764 [Xylella fastidiosa Temecula1]
MRRISQTGQFKRDYKREAKGQHRATLDEELIHVLEALTCDHPLEPRHHDHALTGDWKDHRDCHIKPDLVLIYRKPDNETL
QLVRIGSHSELGL

Nucleotide

• Length: 282 bp

>T20873 NC_004556:1298483-1298764 [Xylella fastidiosa Temecula1]
ATGCGGAGGATTAGCCAGACTGGCCAATTCAAGCGCGACTACAAGCGCGAAGCTAAGGGCCAGCATCGCGCCACGCTTGA
TGAGGAACTGATACACGTCTTGGAAGCCTTGACCTGTGATCATCCGTTGGAGCCACGCCACCACGATCACGCACTAACTG
GCGACTGGAAAGATCACCGTGATTGCCACATCAAACCCGACTTGGTACTGATATACCGGAAGCCCGACAACGAGACATTG
CAGCTCGTGCGCATTGGCTCACACAGCGAACTAGGTTTGTGA

Antitoxin

Protein

• Length: 88 a.a.
• Molecular weight: 9495.95 Da
• Isoelectric Point: 5.6033

>AT20873 WP_004090907.1 NC_004556:1298233-1298496 [Xylella fastidiosa Temecula1]
MSANAVVRARVDAHIKEEASTVLATMGLSVSDAFRMMLTRIAREKALPFEPLVPNETTIAAMREARAGHLKSFDSIEALM
ADLHAED

Nucleotide

• Length: 264 bp

>AT20873 NC_004556:1298233-1298496 [Xylella fastidiosa Temecula1]
ATGTCTGCAAACGCAGTTGTCCGTGCCCGCGTTGACGCGCACATCAAAGAAGAAGCATCAACCGTGCTGGCGACGATGGG
CCTAAGCGTGTCTGATGCGTTCCGTATGATGCTGACCCGCATTGCCCGCGAGAAGGCGCTGCCGTTCGAGCCGCTGGTGC
CGAACGAAACTACCATCGCAGCCATGCGTGAAGCCCGTGCTGGTCACCTCAAGAGCTTTGATAGTATTGAGGCGCTCATG
GCGGACTTGCATGCGGAGGATTAG

Structures

Toxin

• AlphaFold DB: Q87CH1

Antitoxin

• AlphaFold DB: Q87CH2