Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-DnaT
Location 374208..374739 Replicon chromosome
Accession NC_004547
Organism Pectobacterium atrosepticum SCRI1043

Toxin (Protein)


Gene name stbE Uniprot ID Q6DAC9
Locus tag ECA_RS01680 Protein ID WP_011091956.1
Coordinates 374452..374739 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID Q6DAD0
Locus tag ECA_RS01675 Protein ID WP_005975532.1
Coordinates 374208..374462 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECA_RS01655 369540..370130 - 591 WP_011091952.1 DnaA initiator-associating protein DiaA -
ECA_RS01660 370172..370528 - 357 WP_173361618.1 YraN family protein -
ECA_RS01665 370525..372543 - 2019 WP_011091954.1 penicillin-binding protein activator -
ECA_RS01670 372605..373492 + 888 WP_011091955.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
ECA_RS01675 374208..374462 + 255 WP_005975532.1 hypothetical protein Antitoxin
ECA_RS01680 374452..374739 + 288 WP_011091956.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ECA_RS01685 374918..375703 + 786 WP_011091957.1 4,5-DOPA dioxygenase extradiol -
ECA_RS01690 375772..376932 - 1161 WP_011091958.1 glutathionylspermidine synthase family protein -
ECA_RS01695 376944..377618 - 675 WP_011091959.1 DUF1190 family protein -
ECA_RS01700 377889..379283 - 1395 WP_011091960.1 outer membrane channel protein TolC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11012.91 Da        Isoelectric Point: 10.7694

>T20858 WP_011091956.1 NC_004547:374452-374739 [Pectobacterium atrosepticum SCRI1043]
MTYKLKFVPSAMKEWKKLGHPVREQFKKKLAERLDNPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDDTITVMVMGVGK
REGNQIYSDTKGRST

Download         Length: 288 bp

>T20858 NC_004547:374452-374739 [Pectobacterium atrosepticum SCRI1043]
ATGACCTATAAGTTAAAATTTGTGCCTTCTGCAATGAAGGAATGGAAAAAATTAGGGCATCCTGTCCGGGAACAATTCAA
GAAGAAGTTGGCTGAGCGTCTGGATAATCCTCGAGTTCCCTCGGCTCAGCTTCATGGCCGCAAAGATCAGTATAAAATTA
AACTTAAGTCTGCTGGCTACAGACTGGTGTATTTAGTTCAGGATGACACCATTACAGTAATGGTTATGGGGGTTGGGAAG
CGTGAAGGAAATCAGATTTATTCTGATACTAAGGGGCGGTCTACTTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9246.47 Da        Isoelectric Point: 3.9487

>AT20858 WP_005975532.1 NC_004547:374208-374462 [Pectobacterium atrosepticum SCRI1043]
MAFNILTNTAASITELKRDPMGTVRSAEGETIAILNRNEPAFYCVPPAVFAYLMELAEDAELGHTVDERMSEIVDAKEIS
LDDL

Download         Length: 255 bp

>AT20858 NC_004547:374208-374462 [Pectobacterium atrosepticum SCRI1043]
ATGGCTTTCAACATCCTAACTAATACAGCAGCCAGTATCACTGAGTTGAAACGTGACCCAATGGGGACGGTGCGGTCTGC
TGAAGGTGAAACTATTGCTATACTGAATCGCAATGAGCCTGCGTTCTATTGCGTGCCTCCTGCCGTATTCGCTTACTTGA
TGGAACTCGCTGAAGATGCAGAATTGGGGCATACCGTCGATGAGCGGATGTCAGAGATAGTGGATGCGAAAGAGATTTCG
CTCGATGACCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0J5XUG4

Antitoxin

Source ID Structure
AlphaFold DB A0A1D7Z173

References