Detailed information of TA system
Overview
TA module
| Type | IV | Classification (family/domain) | abiEi-abiEii/AbiEii-AbiEi |
| Location | 1408678..1410113 | Replicon | chromosome |
| Accession | NC_004368 | ||
| Organism | Streptococcus agalactiae NEM316 | ||
Toxin (Protein)
| Gene name | abiEi | Uniprot ID | Q8E4P3 |
| Locus tag | GBS_RS07160 | Protein ID | WP_001030310.1 |
| Coordinates | 1409265..1410113 (+) | Length | 283 a.a. |
Antitoxin (Protein)
| Gene name | abiEii | Uniprot ID | Q8E4P4 |
| Locus tag | GBS_RS07155 | Protein ID | WP_000037314.1 |
| Coordinates | 1408678..1409268 (+) | Length | 197 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GBS_RS07155 | 1408678..1409268 | + | 591 | WP_000037314.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
| GBS_RS07160 | 1409265..1410113 | + | 849 | WP_001030310.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| GBS_RS07165 | 1410217..1413012 | - | 2796 | WP_001224271.1 | CHAP domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 283 a.a. Molecular weight: 32622.01 Da Isoelectric Point: 5.6940
>T20814 WP_001030310.1 NC_004368:1409265-1410113 [Streptococcus agalactiae NEM316]
MNKAKLTALCHKISKQTGLTFNSVMTYYFLEVILKKLSQSSYSDHYIFKGGFLLSNVIGVESRSTVDIDFLFNKQTLSGE
SIQRQLTEILAEDSKDDISFSIQSITAIKESDDYGGYRATILCQLENIKQMIHLDIATGDIVTPHPVTYDYKAIFDNKSF
PIIAYTIETILAEKLQTIYSRNFLNSRSKDFYDVYILSKLKRQEINFSQLNIACQRTFSYRDTELNFNKLIELLETFKSD
AIQSQQWQNYSKKYSYTKGISFSDILDEIIDLLTDLNYENNH
MNKAKLTALCHKISKQTGLTFNSVMTYYFLEVILKKLSQSSYSDHYIFKGGFLLSNVIGVESRSTVDIDFLFNKQTLSGE
SIQRQLTEILAEDSKDDISFSIQSITAIKESDDYGGYRATILCQLENIKQMIHLDIATGDIVTPHPVTYDYKAIFDNKSF
PIIAYTIETILAEKLQTIYSRNFLNSRSKDFYDVYILSKLKRQEINFSQLNIACQRTFSYRDTELNFNKLIELLETFKSD
AIQSQQWQNYSKKYSYTKGISFSDILDEIIDLLTDLNYENNH
Download Length: 849 bp
>T20814 NC_004368:1409265-1410113 [Streptococcus agalactiae NEM316]
TTGAACAAGGCAAAATTAACAGCACTCTGCCATAAAATTTCCAAACAAACAGGGCTAACTTTTAATTCAGTAATGACTTA
TTACTTTCTTGAAGTCATTTTGAAAAAGCTCAGTCAAAGTTCTTATTCAGATCACTATATCTTTAAAGGTGGATTTTTGC
TCTCAAATGTTATAGGGGTTGAATCACGCAGTACGGTTGATATTGACTTTCTATTTAATAAACAGACTCTCTCAGGAGAA
AGTATTCAACGACAACTCACAGAAATCTTAGCAGAAGATTCTAAAGATGACATTAGCTTTTCTATTCAATCTATCACTGC
TATTAAAGAAAGTGATGACTATGGAGGCTATCGAGCAACCATTTTATGTCAACTGGAAAATATTAAACAAATGATCCATC
TAGATATTGCAACTGGTGATATTGTTACACCCCACCCCGTTACCTATGACTATAAAGCAATTTTTGATAATAAAAGTTTT
CCAATCATTGCTTATACGATTGAAACAATTTTAGCTGAAAAATTACAAACGATTTACTCAAGAAATTTCTTGAACAGTCG
CAGCAAAGATTTTTACGATGTCTATATCCTATCAAAATTAAAAAGGCAAGAAATCAATTTCTCTCAGCTAAATATCGCCT
GTCAAAGAACCTTTTCTTATCGTGATACCGAGTTAAATTTCAACAAACTCATTGAATTACTAGAAACATTCAAATCCGAT
GCCATTCAAAGTCAACAATGGCAAAACTATTCAAAAAAATATAGTTATACAAAAGGTATTTCCTTTTCAGATATACTTGA
TGAGATTATCGACCTACTAACTGATCTCAATTATGAAAATAATCATTAA
TTGAACAAGGCAAAATTAACAGCACTCTGCCATAAAATTTCCAAACAAACAGGGCTAACTTTTAATTCAGTAATGACTTA
TTACTTTCTTGAAGTCATTTTGAAAAAGCTCAGTCAAAGTTCTTATTCAGATCACTATATCTTTAAAGGTGGATTTTTGC
TCTCAAATGTTATAGGGGTTGAATCACGCAGTACGGTTGATATTGACTTTCTATTTAATAAACAGACTCTCTCAGGAGAA
AGTATTCAACGACAACTCACAGAAATCTTAGCAGAAGATTCTAAAGATGACATTAGCTTTTCTATTCAATCTATCACTGC
TATTAAAGAAAGTGATGACTATGGAGGCTATCGAGCAACCATTTTATGTCAACTGGAAAATATTAAACAAATGATCCATC
TAGATATTGCAACTGGTGATATTGTTACACCCCACCCCGTTACCTATGACTATAAAGCAATTTTTGATAATAAAAGTTTT
CCAATCATTGCTTATACGATTGAAACAATTTTAGCTGAAAAATTACAAACGATTTACTCAAGAAATTTCTTGAACAGTCG
CAGCAAAGATTTTTACGATGTCTATATCCTATCAAAATTAAAAAGGCAAGAAATCAATTTCTCTCAGCTAAATATCGCCT
GTCAAAGAACCTTTTCTTATCGTGATACCGAGTTAAATTTCAACAAACTCATTGAATTACTAGAAACATTCAAATCCGAT
GCCATTCAAAGTCAACAATGGCAAAACTATTCAAAAAAATATAGTTATACAAAAGGTATTTCCTTTTCAGATATACTTGA
TGAGATTATCGACCTACTAACTGATCTCAATTATGAAAATAATCATTAA
Antitoxin
Download Length: 197 a.a. Molecular weight: 23040.43 Da Isoelectric Point: 6.7184
>AT20814 WP_000037314.1 NC_004368:1408678-1409268 [Streptococcus agalactiae NEM316]
MSKKEMLFDYLENHNGMITSKDCKTIGIPTIYLTRLENEGVIFRVEKGIYLSSTGDYDEYYFFQYRYPRTVFSYVSALYL
QGFTDEIPQYFEITVPKGYRFRNTPLNLNIHTVSKEFVNLGVISVETPVGNIVKVHDFERILCDFILNRDKIDSELFVKT
LQTYSNYSKKNTGKLYEYATKMNILDEVKRTLEVLL
MSKKEMLFDYLENHNGMITSKDCKTIGIPTIYLTRLENEGVIFRVEKGIYLSSTGDYDEYYFFQYRYPRTVFSYVSALYL
QGFTDEIPQYFEITVPKGYRFRNTPLNLNIHTVSKEFVNLGVISVETPVGNIVKVHDFERILCDFILNRDKIDSELFVKT
LQTYSNYSKKNTGKLYEYATKMNILDEVKRTLEVLL
Download Length: 591 bp
>AT20814 NC_004368:1408678-1409268 [Streptococcus agalactiae NEM316]
ATGTCTAAAAAAGAAATGTTATTTGACTATTTAGAAAATCACAATGGCATGATTACTTCTAAAGATTGTAAAACAATAGG
CATTCCAACAATATATCTGACAAGACTAGAAAACGAAGGAGTTATCTTTCGGGTTGAAAAAGGCATTTATCTATCATCTA
CTGGGGATTATGATGAATACTATTTCTTTCAATATCGTTATCCCAGAACTGTTTTTTCTTACGTCTCTGCTCTTTATCTA
CAAGGGTTTACAGATGAAATTCCTCAATACTTTGAAATAACGGTTCCAAAAGGTTACCGTTTCAGGAATACTCCATTGAA
TCTCAATATTCACACTGTTTCTAAAGAATTTGTTAATCTTGGAGTTATTAGTGTAGAAACTCCTGTGGGAAACATTGTCA
AAGTTCACGATTTTGAACGTATTCTATGCGATTTTATCCTTAACCGAGATAAAATTGATTCTGAGCTCTTTGTCAAAACA
CTTCAAACTTATAGCAACTATTCTAAAAAAAATACTGGGAAACTCTATGAATACGCTACAAAAATGAACATCCTAGATGA
AGTCAAACGAACCTTGGAGGTACTACTTTGA
ATGTCTAAAAAAGAAATGTTATTTGACTATTTAGAAAATCACAATGGCATGATTACTTCTAAAGATTGTAAAACAATAGG
CATTCCAACAATATATCTGACAAGACTAGAAAACGAAGGAGTTATCTTTCGGGTTGAAAAAGGCATTTATCTATCATCTA
CTGGGGATTATGATGAATACTATTTCTTTCAATATCGTTATCCCAGAACTGTTTTTTCTTACGTCTCTGCTCTTTATCTA
CAAGGGTTTACAGATGAAATTCCTCAATACTTTGAAATAACGGTTCCAAAAGGTTACCGTTTCAGGAATACTCCATTGAA
TCTCAATATTCACACTGTTTCTAAAGAATTTGTTAATCTTGGAGTTATTAGTGTAGAAACTCCTGTGGGAAACATTGTCA
AAGTTCACGATTTTGAACGTATTCTATGCGATTTTATCCTTAACCGAGATAAAATTGATTCTGAGCTCTTTGTCAAAACA
CTTCAAACTTATAGCAACTATTCTAAAAAAAATACTGGGAAACTCTATGAATACGCTACAAAAATGAACATCCTAGATGA
AGTCAAACGAACCTTGGAGGTACTACTTTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|