Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | cptAB/Cpta(toxin) |
Location | 3251380..3252046 | Replicon | chromosome |
Accession | NZ_CP077850 | ||
Organism | Erwinia amylovora strain CP200242 isolate missinsg |
Toxin (Protein)
Gene name | cptA | Uniprot ID | A0A830ZTB8 |
Locus tag | KTR61_RS14685 | Protein ID | WP_004161808.1 |
Coordinates | 3251380..3251799 (-) | Length | 140 a.a. |
Antitoxin (Protein)
Gene name | cptB | Uniprot ID | D4HWC2 |
Locus tag | KTR61_RS14690 | Protein ID | WP_004155593.1 |
Coordinates | 3251780..3252046 (-) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
KTR61_RS14670 (KTR61_14645) | 3247372..3249051 | + | 1680 | WP_004155599.1 | type III effector | - |
KTR61_RS14675 (KTR61_14650) | 3249561..3250514 | + | 954 | WP_004155597.1 | DMT family transporter | - |
KTR61_RS14680 (KTR61_14655) | 3250744..3251262 | + | 519 | WP_004155596.1 | flavodoxin FldB | - |
KTR61_RS14685 (KTR61_14660) | 3251380..3251799 | - | 420 | WP_004161808.1 | protein YgfX | Toxin |
KTR61_RS14690 (KTR61_14665) | 3251780..3252046 | - | 267 | WP_004155593.1 | FAD assembly factor SdhE | Antitoxin |
KTR61_RS14695 (KTR61_14670) | 3252272..3253258 | + | 987 | WP_004155590.1 | tRNA-modifying protein YgfZ | - |
KTR61_RS14700 (KTR61_14675) | 3253259..3253918 | - | 660 | WP_004155588.1 | hemolysin III family protein | - |
KTR61_RS14705 (KTR61_14680) | 3254131..3254739 | + | 609 | WP_004155587.1 | HD domain-containing protein | - |
KTR61_RS14710 (KTR61_14685) | 3254844..3255573 | - | 730 | Protein_2834 | SDR family oxidoreductase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 140 a.a. Molecular weight: 16366.46 Da Isoelectric Point: 11.9444
>T208077 WP_004161808.1 NZ_CP077850:c3251799-3251380 [Erwinia amylovora]
VVLWQCELRPSRLAQRFSLLLHGAVMLALLLPTWPASSGLVRMLLLVLVLLECIRSRRRIGRRQGDIALLEGHELRWRQR
EWCIISRPWLTGQAILLLLQDTHGQRERLWLFADGMEKRNWRQLRLQLLNSKVQGNGWC
VVLWQCELRPSRLAQRFSLLLHGAVMLALLLPTWPASSGLVRMLLLVLVLLECIRSRRRIGRRQGDIALLEGHELRWRQR
EWCIISRPWLTGQAILLLLQDTHGQRERLWLFADGMEKRNWRQLRLQLLNSKVQGNGWC
Download Length: 420 bp
>T208077 NZ_CP103562:c4314975-4314688 [Escherichia coli O25b:H4-ST131]
ATGCCAATGGAGTTTGAATGGGATGCAAACAAGGCCAAAAGTAATCGGGTGAAACATGGCATCCGCTTTGAAGATGCGGT
GTTAGTGTTTGATGATCCACAACATTTGTCACAGCAAGATCGCATAGAAAACGGTGAGTATCGCTGGCAGACTATCGGCC
TGGTTCACGGTATCGTGGTTATTCTGGTTGCGCATACCATCCGTTTCGAAAGCGGAAATGAAATTATTCGAATCATCAGT
GCACGAAAAGCAGATCGTAAAGAGAGGAGCCGCTATGAGCATGGTTAA
ATGCCAATGGAGTTTGAATGGGATGCAAACAAGGCCAAAAGTAATCGGGTGAAACATGGCATCCGCTTTGAAGATGCGGT
GTTAGTGTTTGATGATCCACAACATTTGTCACAGCAAGATCGCATAGAAAACGGTGAGTATCGCTGGCAGACTATCGGCC
TGGTTCACGGTATCGTGGTTATTCTGGTTGCGCATACCATCCGTTTCGAAAGCGGAAATGAAATTATTCGAATCATCAGT
GCACGAAAAGCAGATCGTAAAGAGAGGAGCCGCTATGAGCATGGTTAA
Antitoxin
Download Length: 89 a.a. Molecular weight: 10498.07 Da Isoelectric Point: 6.4605
>AT208077 WP_004155593.1 NZ_CP077850:c3252046-3251780 [Erwinia amylovora]
MDITNKSRIHWACRRGMRELDISIMPFFQYEFDSLNDSDKRLFVRLLESDDPDLFNWLMNHGEPADVELKRMVALIQQRN
KQRGPVAM
MDITNKSRIHWACRRGMRELDISIMPFFQYEFDSLNDSDKRLFVRLLESDDPDLFNWLMNHGEPADVELKRMVALIQQRN
KQRGPVAM
Download Length: 267 bp
>AT208077 NZ_CP103562:c4314701-4314399 [Escherichia coli O25b:H4-ST131]
ATGAGCATGGTTAAACATAAACGAGGGACACCCTCTACACTCGATGTGCAGCATGAGGCCGAACTGAAGGCACTGGCGAA
TAAATTCGACGAAGATATTGATTACAGTGATATCCCGCCTTCCAGCGATGAGCAATGGTCTAACGCAGAACGCGGTAAGT
TTTATCGGCCATTGAAAACCCAGGCTTCGGTGCGTATTGATGCTGATGTGATGGAATGGCTGAAGCGACCTGGTAAAGGC
TATCAAACTCGCCTGAACGCAATTTTACGTGAAGCGATGCTGCGCGATCAGAACAAAAAATAA
ATGAGCATGGTTAAACATAAACGAGGGACACCCTCTACACTCGATGTGCAGCATGAGGCCGAACTGAAGGCACTGGCGAA
TAAATTCGACGAAGATATTGATTACAGTGATATCCCGCCTTCCAGCGATGAGCAATGGTCTAACGCAGAACGCGGTAAGT
TTTATCGGCCATTGAAAACCCAGGCTTCGGTGCGTATTGATGCTGATGTGATGGAATGGCTGAAGCGACCTGGTAAAGGC
TATCAAACTCGCCTGAACGCAATTTTACGTGAAGCGATGCTGCGCGATCAGAACAAAAAATAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A830ZTB8 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A831A3F0 |