Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3250878..3251023 Replicon chromosome
Accession NZ_CP077824
Organism Klebsiella pneumoniae strain FF1009

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3250885..3250987 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3250878..3251023 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KU661_RS15785 (KU661_15725) 3246410..3247843 + 1434 WP_117045278.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
KU661_RS15790 (KU661_15730) 3247959..3248198 + 240 WP_002911393.1 YebV family protein -
KU661_RS15795 (KU661_15735) 3248296..3248487 + 192 WP_002911395.1 YebW family protein -
KU661_RS15800 (KU661_15740) 3248484..3249137 - 654 WP_020804905.1 protein-serine/threonine phosphatase -
KU661_RS15805 (KU661_15745) 3249294..3250262 + 969 WP_004151446.1 VirK/YbjX family protein -
KU661_RS15810 (KU661_15750) 3250367..3250510 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3250878..3251023 + 146 - - Antitoxin
- 3250885..3250987 - 103 - - Toxin
KU661_RS15815 (KU661_15755) 3251146..3251484 - 339 WP_002911404.1 YebY family protein -
KU661_RS15820 (KU661_15760) 3251501..3252370 - 870 WP_004175431.1 copper homeostasis membrane protein CopD -
KU661_RS15825 (KU661_15765) 3252374..3252748 - 375 WP_004151448.1 CopC domain-containing protein YobA -
KU661_RS15830 (KU661_15770) 3252861..3253091 + 231 WP_002911406.1 DNA polymerase III subunit theta -
KU661_RS15835 (KU661_15775) 3253170..3253829 + 660 WP_021440386.1 exodeoxyribonuclease X -
KU661_RS15840 (KU661_15780) 3253833..3255893 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T208033 NZ_CP077824:c3250987-3250885 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT208033 NZ_CP077824:3250878-3251023 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References