Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 5123800..5123945 Replicon chromosome
Accession NZ_CP077818
Organism Klebsiella pneumoniae strain FF1023

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 5123807..5123909 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 5123800..5123945 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KU670_RS24685 (KU670_24650) 5119332..5120765 + 1434 WP_087831866.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
KU670_RS24690 (KU670_24655) 5120881..5121120 + 240 WP_002911393.1 YebV family protein -
KU670_RS24695 (KU670_24660) 5121218..5121409 + 192 WP_002911395.1 YebW family protein -
KU670_RS24700 (KU670_24665) 5121406..5122059 - 654 WP_019725444.1 protein-serine/threonine phosphatase -
KU670_RS24705 (KU670_24670) 5122216..5123184 + 969 WP_004151446.1 VirK/YbjX family protein -
KU670_RS24710 (KU670_24675) 5123289..5123432 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 5123800..5123945 + 146 - - Antitoxin
- 5123807..5123909 - 103 - - Toxin
KU670_RS24715 (KU670_24680) 5124068..5124406 - 339 WP_002911404.1 YebY family protein -
KU670_RS24720 (KU670_24685) 5124423..5125292 - 870 WP_004175431.1 copper homeostasis membrane protein CopD -
KU670_RS24725 (KU670_24690) 5125296..5125670 - 375 WP_004151448.1 CopC domain-containing protein YobA -
KU670_RS24730 (KU670_24695) 5125783..5126013 + 231 WP_002911406.1 DNA polymerase III subunit theta -
KU670_RS24735 (KU670_24700) 5126092..5126751 + 660 WP_040224088.1 exodeoxyribonuclease X -
KU670_RS24740 (KU670_24705) 5126755..5128815 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T207982 NZ_CP077818:c5123909-5123807 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT207982 NZ_CP077818:5123800-5123945 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References