Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 674492..674637 Replicon chromosome
Accession NZ_CP077812
Organism Klebsiella pneumoniae strain FF1083

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 674528..674630 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 674492..674637 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KU672_RS03160 669622..671682 + 2061 WP_004151449.1 oligopeptidase B -
KU672_RS03165 671686..672345 - 660 WP_002911407.1 exodeoxyribonuclease X -
KU672_RS03170 672424..672654 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KU672_RS03175 672767..673141 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KU672_RS03180 673145..674014 + 870 WP_064148102.1 copper homeostasis membrane protein CopD -
KU672_RS03185 674031..674369 + 339 WP_002911404.1 YebY family protein -
- 674492..674637 - 146 - - Antitoxin
- 674528..674630 + 103 - - Toxin
KU672_RS03190 675006..675149 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KU672_RS03195 675254..676222 - 969 WP_014907334.1 VirK/YbjX family protein -
KU672_RS03200 676379..677032 + 654 WP_004175436.1 protein-serine/threonine phosphatase -
KU672_RS03205 677029..677220 - 192 WP_002911395.1 YebW family protein -
KU672_RS03210 677318..677557 - 240 WP_002911393.1 YebV family protein -
KU672_RS03215 677673..679106 - 1434 WP_021440382.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T207912 NZ_CP077812:674528-674630 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT207912 NZ_CP077812:c674637-674492 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References