Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 636201..636346 Replicon chromosome
Accession NZ_CP077806
Organism Klebsiella pneumoniae strain FF979

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 636237..636339 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 636201..636346 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KU665_RS02895 (KU665_02900) 631331..633391 + 2061 WP_251336020.1 oligopeptidase B -
KU665_RS02900 (KU665_02905) 633395..634054 - 660 WP_002911407.1 exodeoxyribonuclease X -
KU665_RS02905 (KU665_02910) 634133..634363 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KU665_RS02910 (KU665_02915) 634476..634850 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KU665_RS02915 (KU665_02920) 634854..635723 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
KU665_RS02920 (KU665_02925) 635740..636078 + 339 WP_064172944.1 YebY family protein -
- 636201..636346 - 146 - - Antitoxin
- 636237..636339 + 103 - - Toxin
KU665_RS02925 (KU665_02930) 636714..636857 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KU665_RS02930 (KU665_02935) 636962..637930 - 969 WP_073972692.1 VirK/YbjX family protein -
KU665_RS02935 (KU665_02940) 638087..638740 + 654 WP_094310679.1 protein-serine/threonine phosphatase -
KU665_RS02940 (KU665_02945) 638737..638928 - 192 WP_002911395.1 YebW family protein -
KU665_RS02945 (KU665_02950) 639026..639265 - 240 WP_002911393.1 YebV family protein -
KU665_RS02950 (KU665_02955) 639381..640814 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T207854 NZ_CP077806:636237-636339 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT207854 NZ_CP077806:c636346-636201 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References