Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2668333..2668477 Replicon chromosome
Accession NZ_CP077805
Organism Klebsiella variicola strain FF907

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2668369..2668471 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2668333..2668477 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KU664_RS12980 (KU664_12950) 2663463..2665523 + 2061 WP_012541258.1 oligopeptidase B -
KU664_RS12985 (KU664_12955) 2665527..2666186 - 660 WP_008804267.1 exodeoxyribonuclease X -
KU664_RS12990 (KU664_12960) 2666265..2666495 - 231 WP_012541260.1 DNA polymerase III subunit theta -
KU664_RS12995 (KU664_12965) 2666609..2666983 + 375 WP_038421459.1 CopC domain-containing protein YobA -
KU664_RS13000 (KU664_12970) 2666987..2667856 + 870 WP_100780970.1 copper homeostasis membrane protein CopD -
KU664_RS13005 (KU664_12975) 2667873..2668211 + 339 WP_008804271.1 YebY family protein -
- 2668333..2668477 - 145 - - Antitoxin
- 2668369..2668471 + 103 - - Toxin
KU664_RS13010 (KU664_12980) 2668856..2668999 - 144 WP_046621074.1 Ecr family regulatory small membrane protein -
KU664_RS13015 (KU664_12985) 2669103..2670071 - 969 WP_162493241.1 VirK/YbjX family protein -
KU664_RS13020 (KU664_12990) 2670227..2670880 + 654 WP_008804273.1 protein-serine/threonine phosphatase -
KU664_RS13025 (KU664_12995) 2670877..2671068 - 192 WP_002911395.1 YebW family protein -
KU664_RS13030 (KU664_13000) 2671166..2671405 - 240 WP_002911393.1 YebV family protein -
KU664_RS13035 (KU664_13005) 2671521..2672954 - 1434 WP_008804274.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T207842 NZ_CP077805:2668369-2668471 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT207842 NZ_CP077805:c2668477-2668333 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References