Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1945086..1945231 Replicon chromosome
Accession NZ_CP077779
Organism Klebsiella pneumoniae strain CDI231

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1945122..1945224 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1945086..1945231 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KUM55_RS09370 (KUM55_09375) 1940216..1942276 + 2061 WP_004148850.1 oligopeptidase B -
KUM55_RS09375 (KUM55_09380) 1942280..1942939 - 660 WP_002911407.1 exodeoxyribonuclease X -
KUM55_RS09380 (KUM55_09385) 1943018..1943248 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KUM55_RS09385 (KUM55_09390) 1943361..1943735 + 375 WP_071058708.1 CopC domain-containing protein YobA -
KUM55_RS09390 (KUM55_09395) 1943739..1944608 + 870 WP_032420215.1 copper homeostasis membrane protein CopD -
KUM55_RS09395 (KUM55_09400) 1944625..1944963 + 339 WP_002911404.1 YebY family protein -
- 1945086..1945231 - 146 - - Antitoxin
- 1945122..1945224 + 103 - - Toxin
KUM55_RS09400 (KUM55_09405) 1945599..1945742 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KUM55_RS09405 (KUM55_09410) 1945847..1946815 - 969 WP_073971755.1 VirK/YbjX family protein -
KUM55_RS09410 (KUM55_09415) 1946972..1947625 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
KUM55_RS09415 (KUM55_09420) 1947622..1947813 - 192 WP_002911395.1 YebW family protein -
KUM55_RS09420 (KUM55_09425) 1947911..1948150 - 240 WP_002911393.1 YebV family protein -
KUM55_RS09425 (KUM55_09430) 1948266..1949699 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T207802 NZ_CP077779:1945122-1945224 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT207802 NZ_CP077779:c1945231-1945086 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References