Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1836495..1836640 Replicon chromosome
Accession NZ_CP077763
Organism Klebsiella pneumoniae strain KP63

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1836502..1836604 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1836495..1836640 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KQQ01_RS09295 1832027..1833460 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
KQQ01_RS09300 1833576..1833815 + 240 WP_002911393.1 YebV family protein -
KQQ01_RS09305 1833913..1834104 + 192 WP_002911395.1 YebW family protein -
KQQ01_RS09310 1834101..1834754 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
KQQ01_RS09315 1834911..1835879 + 969 WP_004151446.1 VirK/YbjX family protein -
KQQ01_RS09320 1835984..1836127 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 1836495..1836640 + 146 - - Antitoxin
- 1836502..1836604 - 103 - - Toxin
KQQ01_RS09325 1836763..1837101 - 339 WP_002911404.1 YebY family protein -
KQQ01_RS09330 1837118..1837987 - 870 WP_062955019.1 copper homeostasis membrane protein CopD -
KQQ01_RS09335 1837991..1838365 - 375 WP_004151448.1 CopC domain-containing protein YobA -
KQQ01_RS09340 1838478..1838708 + 231 WP_002911406.1 DNA polymerase III subunit theta -
KQQ01_RS09345 1838787..1839446 + 660 WP_002911407.1 exodeoxyribonuclease X -
KQQ01_RS09350 1839450..1841510 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T207753 NZ_CP077763:c1836604-1836502 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT207753 NZ_CP077763:1836495-1836640 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References