Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | phd-doc/Doc-RelB |
Location | 2762747..2763333 | Replicon | chromosome |
Accession | NZ_CP077760 | ||
Organism | Salmonella enterica subsp. enterica serovar Gallinarum strain 07Q015 |
Toxin (Protein)
Gene name | doc | Uniprot ID | B5RGW8 |
Locus tag | KTV86_RS13265 | Protein ID | WP_001576508.1 |
Coordinates | 2762965..2763333 (+) | Length | 123 a.a. |
Antitoxin (Protein)
Gene name | phd | Uniprot ID | V7IU48 |
Locus tag | KTV86_RS13260 | Protein ID | WP_001522145.1 |
Coordinates | 2762747..2762968 (+) | Length | 74 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
KTV86_RS13235 (2757768) | 2757768..2758877 | + | 1110 | WP_000822976.1 | high-affinity branched-chain amino acid ABC transporter substrate-binding protein LivK | - |
KTV86_RS13240 (2758937) | 2758937..2759863 | + | 927 | WP_000003007.1 | high-affinity branched-chain amino acid ABC transporter permease LivH | - |
KTV86_RS13245 (2759860) | 2759860..2761137 | + | 1278 | WP_000803768.1 | branched chain amino acid ABC transporter permease LivM | - |
KTV86_RS13250 (2761134) | 2761134..2761901 | + | 768 | WP_000082080.1 | high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivG | - |
KTV86_RS13255 (2761903) | 2761903..2762616 | + | 714 | WP_000416114.1 | high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF | - |
KTV86_RS13260 (2762747) | 2762747..2762968 | + | 222 | WP_001522145.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
KTV86_RS13265 (2762965) | 2762965..2763333 | + | 369 | WP_001576508.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin |
KTV86_RS13270 (2763592) | 2763592..2764908 | + | 1317 | WP_223671629.1 | sn-glycerol-3-phosphate ABC transporter substrate-binding protein UgpB | - |
KTV86_RS13275 (2765013) | 2765013..2765900 | + | 888 | WP_000099303.1 | sn-glycerol-3-phosphate ABC transporter permease UgpA | - |
KTV86_RS13280 (2765897) | 2765897..2766742 | + | 846 | WP_000572197.1 | sn-glycerol-3-phosphate ABC transporter permease UgpE | - |
KTV86_RS13285 (2766744) | 2766744..2767814 | + | 1071 | WP_000907833.1 | sn-glycerol-3-phosphate import ATP-binding protein UgpC | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 2757768..2768548 | 10780 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 123 a.a. Molecular weight: 13662.01 Da Isoelectric Point: 6.7252
>T207745 WP_001576508.1 NZ_CP077760:2762965-2763333 [Salmonella enterica subsp. enterica serovar Gallinarum]
MTLQLISAEEIIQFHDRLLRVTPGVTGMPDPGRAEALMYRVLNQIEYEGVTDVWLLAAMHLLAIFRGHIFNDGNKRTALF
ITLLFLKRNGISLAANPDFVDMTVDAAAGRLTLEQIVVRLRA
MTLQLISAEEIIQFHDRLLRVTPGVTGMPDPGRAEALMYRVLNQIEYEGVTDVWLLAAMHLLAIFRGHIFNDGNKRTALF
ITLLFLKRNGISLAANPDFVDMTVDAAAGRLTLEQIVVRLRA
Download Length: 369 bp
>T207745 NZ_CP103503:2044442-2044544 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 74 a.a. Molecular weight: 8166.17 Da Isoelectric Point: 5.0775
>AT207745 WP_001522145.1 NZ_CP077760:2762747-2762968 [Salmonella enterica subsp. enterica serovar Gallinarum]
MRTVNYSEARQNLAEVLESAVTAGPVTITRRGHKSAVIISAEEFERYQTARMDDEFAAIMAVHGNELRELADK
MRTVNYSEARQNLAEVLESAVTAGPVTITRRGHKSAVIISAEEFERYQTARMDDEFAAIMAVHGNELRELADK
Download Length: 222 bp
>AT207745 NZ_CP103503:c2044551-2044406 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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