Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1705584..1706115 Replicon chromosome
Accession NZ_CP077745
Organism Desulfovibrio desulfuricans strain Edelweiss

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KUD97_RS07305 Protein ID WP_233482535.1
Coordinates 1705584..1705880 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KUD97_RS07310 Protein ID WP_233482536.1
Coordinates 1705870..1706115 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KUD97_RS07280 (KUD97_07275) 1701039..1702736 - 1698 WP_233482530.1 VWA domain-containing protein -
KUD97_RS07285 (KUD97_07280) 1702862..1703125 - 264 WP_233482531.1 hypothetical protein -
KUD97_RS07290 (KUD97_07285) 1703157..1704191 - 1035 WP_233482532.1 DUF3150 domain-containing protein -
KUD97_RS07295 (KUD97_07290) 1704207..1705226 - 1020 WP_233482533.1 AAA family ATPase -
KUD97_RS07300 (KUD97_07295) 1705325..1705525 - 201 WP_233482534.1 hypothetical protein -
KUD97_RS07305 (KUD97_07300) 1705584..1705880 - 297 WP_233482535.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KUD97_RS07310 (KUD97_07305) 1705870..1706115 - 246 WP_233482536.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
KUD97_RS07315 (KUD97_07310) 1706173..1706541 - 369 WP_233482537.1 ERF family protein -
KUD97_RS07320 (KUD97_07315) 1706830..1710084 + 3255 WP_233482538.1 type I restriction-modification system endonuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1665083..1740592 75509


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-69)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11649.65 Da        Isoelectric Point: 10.4983

>T207693 WP_233482535.1 NZ_CP077745:c1705880-1705584 [Desulfovibrio desulfuricans]
MSYSLQFHELALKEWKKLDASIREQFKKKLAERLQQPRVPSSALSGMRDCYKIKLRSIGYRLVYKVNDDILFVTVISIGK
RERLEAYRQALRRMPSEE

Download         Length: 297 bp

>T207693 NZ_CP103479:2632937-2634259 [Escherichia coli]
ATGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAATGGCGCGCACACCTTTAA
GTATGCACCGGAGTGGTTAGCCAACCGTTATGCCAGACCGTTATCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CTGATGCTGTATTTAACTTCTTCGATAACCTGCTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCTAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGATAGCGTTGGTGCCGTAACGTTATTACCCGAAAA
TGAAACCATAACGCGCCCGATAATGGCATGGGAACAGCTCACTGAAGCCAGGCTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCTCTGGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCGCAGGAGAAGACAGCGCTG
CTCAGAATAGGCAATGACTGGTGCATTCCGAAAGGAATAACGCCGACGACGCACATCATTAAATTACCGATTGGCGAAAT
CAGGCAGCCCAATGCGACGCTCGATCTCAGCCAAAGCGTTGATAATGAGTATTACTGTCTGCTGCTGGCGAAAGAACTTG
GGTTGAATGTGCCGGACGCAGAAATCATTAAAGCGGGAAATGTGCGCGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATGCTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGTCAGACATTCGGTTTACCTTCATCGGTGAAATA
TGAATCAGATGGAGGCCCAGGCATCGCGCGGATCATGGCTTTTTTGATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATG
ATTTTATGAAGTTTCAGGTGTTCCAGTGGTTGATTGGCGCAACGGATGGCCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGACTCACGCCATTTTACGACATCATTTCAGCATTTCCGGTATTGGGTGGCGCAGGAATACACAT
CAGCGATCTCAAACTAGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTCTGGCGACAGCAAAGGTGCTGAAATTTCCGGAAGTGCAGATGCATGAAATCCTGAGTGACTTTGCCAGAATGATTCCG
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAACCAATGTGTT
GAGGTTGCACGGCCGGTTAAGCCGAGAATACGGTATTAAGTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9116.40 Da        Isoelectric Point: 4.8380

>AT207693 WP_233482536.1 NZ_CP077745:c1706115-1705870 [Desulfovibrio desulfuricans]
MDSIHSNITVSVTELKRNFANVLATAKDAPVAVLNHNKPEAYLLSAKHYEEILGILEDLEDRKVVEKREDGPFIKVTLDE
L

Download         Length: 246 bp

>AT207693 NZ_CP103479:2632671-2632937 [Escherichia coli]
ATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTAGCGAATGCAATGAAACTGGTTCGTCAGCAAAATGGCTGGAC
GCAGAGCGGGCTGGCGAAAAAAATCGGCATTAAGCAGGCGACAATTTCCAATTTCGAAAACAACCCTGACAATACCACGC
TGACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACGCTATGCGACACGAAAAATGCCTCGCCAGAATCA
ACAGAACAGCAAGATCTGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References