Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/- |
| Location | 2964250..2965526 | Replicon | chromosome |
| Accession | NC_004129 | ||
| Organism | Pseudomonas protegens Pf-5 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | Q4KD87 |
| Locus tag | PFL_RS13575 | Protein ID | WP_011060985.1 |
| Coordinates | 2964927..2965526 (+) | Length | 200 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | PFL_RS13570 | Protein ID | WP_011060984.1 |
| Coordinates | 2964250..2964807 (+) | Length | 186 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PFL_RS13540 | 2959454..2960104 | + | 651 | WP_011060978.1 | DUF2239 family protein | - |
| PFL_RS13545 | 2960192..2960812 | + | 621 | WP_011060979.1 | LysE family translocator | - |
| PFL_RS13550 | 2960858..2961445 | - | 588 | WP_011060980.1 | inclusion body family protein | - |
| PFL_RS13555 | 2961905..2963092 | + | 1188 | WP_011060981.1 | hypothetical protein | - |
| PFL_RS13560 | 2963271..2963681 | - | 411 | WP_041774583.1 | hypothetical protein | - |
| PFL_RS13565 | 2963719..2964060 | - | 342 | WP_011060983.1 | low molecular weight protein tyrosine phosphatase family protein | - |
| PFL_RS13570 | 2964250..2964807 | + | 558 | WP_011060984.1 | helix-turn-helix domain-containing protein | Antitoxin |
| PFL_RS13575 | 2964927..2965526 | + | 600 | WP_011060985.1 | HD domain-containing protein | Toxin |
| PFL_RS13580 | 2965740..2967920 | + | 2181 | WP_011060986.1 | catalase/peroxidase HPI | - |
| PFL_RS13585 | 2967982..2968668 | - | 687 | WP_011060987.1 | hypothetical protein | - |
| PFL_RS13590 | 2968628..2969248 | - | 621 | WP_011060988.1 | hypothetical protein | - |
| PFL_RS13595 | 2969296..2969724 | - | 429 | WP_011060989.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 200 a.a. Molecular weight: 22413.22 Da Isoelectric Point: 5.8382
>T20768 WP_011060985.1 NC_004129:2964927-2965526 [Pseudomonas protegens Pf-5]
MNSELLSGRLEFLREAEKLKDVLRSAHTSSGRQESTAEHSWRLCLMALLFEDQLGDLDLLRVLKLCIVHDLGEAIHGDIP
AVAQAAHPDKSPQERADLQLLARALDAPAREHLLELWDEYEGAASNEARAVKALDKLETLLQHTQGQNPAGFDYRFNLGY
GRRYTDASPLFQALRQQIDADTQRRLDAQAQAAVQHRLR
MNSELLSGRLEFLREAEKLKDVLRSAHTSSGRQESTAEHSWRLCLMALLFEDQLGDLDLLRVLKLCIVHDLGEAIHGDIP
AVAQAAHPDKSPQERADLQLLARALDAPAREHLLELWDEYEGAASNEARAVKALDKLETLLQHTQGQNPAGFDYRFNLGY
GRRYTDASPLFQALRQQIDADTQRRLDAQAQAAVQHRLR
Download Length: 600 bp
>T20768 NC_004129:2964927-2965526 [Pseudomonas protegens Pf-5]
ATGAACAGTGAACTTCTCAGTGGCCGCCTTGAATTCCTCCGTGAAGCGGAAAAACTCAAGGACGTGCTGCGCAGTGCCCA
CACCTCCAGCGGCCGCCAGGAAAGCACCGCCGAGCACAGCTGGCGCCTGTGCCTGATGGCGCTGCTGTTCGAAGACCAAC
TGGGGGATCTGGACCTACTGCGGGTGCTGAAGCTGTGCATCGTTCACGACCTGGGGGAGGCCATTCACGGCGATATCCCG
GCGGTGGCCCAGGCCGCCCACCCGGACAAGAGCCCGCAGGAGCGCGCGGACCTGCAACTGCTGGCCCGAGCCCTGGACGC
CCCGGCCCGCGAGCACCTGCTGGAGCTGTGGGACGAATACGAAGGCGCCGCCAGCAACGAGGCGCGCGCGGTCAAGGCCC
TGGACAAGCTGGAAACCCTGCTGCAACACACCCAGGGCCAGAACCCGGCGGGTTTCGACTACCGCTTCAACCTCGGCTAC
GGCCGCCGCTACACCGATGCCAGCCCGCTGTTCCAGGCCCTGCGCCAGCAGATCGATGCCGACACCCAGCGCCGCCTGGA
CGCCCAGGCTCAGGCCGCGGTTCAGCATCGGCTGCGCTAA
ATGAACAGTGAACTTCTCAGTGGCCGCCTTGAATTCCTCCGTGAAGCGGAAAAACTCAAGGACGTGCTGCGCAGTGCCCA
CACCTCCAGCGGCCGCCAGGAAAGCACCGCCGAGCACAGCTGGCGCCTGTGCCTGATGGCGCTGCTGTTCGAAGACCAAC
TGGGGGATCTGGACCTACTGCGGGTGCTGAAGCTGTGCATCGTTCACGACCTGGGGGAGGCCATTCACGGCGATATCCCG
GCGGTGGCCCAGGCCGCCCACCCGGACAAGAGCCCGCAGGAGCGCGCGGACCTGCAACTGCTGGCCCGAGCCCTGGACGC
CCCGGCCCGCGAGCACCTGCTGGAGCTGTGGGACGAATACGAAGGCGCCGCCAGCAACGAGGCGCGCGCGGTCAAGGCCC
TGGACAAGCTGGAAACCCTGCTGCAACACACCCAGGGCCAGAACCCGGCGGGTTTCGACTACCGCTTCAACCTCGGCTAC
GGCCGCCGCTACACCGATGCCAGCCCGCTGTTCCAGGCCCTGCGCCAGCAGATCGATGCCGACACCCAGCGCCGCCTGGA
CGCCCAGGCTCAGGCCGCGGTTCAGCATCGGCTGCGCTAA
Antitoxin
Download Length: 186 a.a. Molecular weight: 20446.44 Da Isoelectric Point: 7.4189
>AT20768 WP_011060984.1 NC_004129:2964250-2964807 [Pseudomonas protegens Pf-5]
MSVALFTSPHLGLALRRWRLLHRVKQQHAAELFGVAQSSISRWENGRQAMEPAERARLEQLLAANLSAAADQALARLVHD
SPRAVHLVCDLTHRLLACSVTRAGQFGVPLSELLGQSLWGFCTEEIVRKEAALDDLGWREVLAPPSLEFFSGHNDSAIVP
IAPSQCRWTRLNLSDGNAVRLVETL
MSVALFTSPHLGLALRRWRLLHRVKQQHAAELFGVAQSSISRWENGRQAMEPAERARLEQLLAANLSAAADQALARLVHD
SPRAVHLVCDLTHRLLACSVTRAGQFGVPLSELLGQSLWGFCTEEIVRKEAALDDLGWREVLAPPSLEFFSGHNDSAIVP
IAPSQCRWTRLNLSDGNAVRLVETL
Download Length: 558 bp
>AT20768 NC_004129:2964250-2964807 [Pseudomonas protegens Pf-5]
ATGTCCGTAGCTCTGTTCACCTCACCCCATCTGGGCCTGGCCCTCAGGCGCTGGCGCCTGTTGCACCGGGTCAAGCAGCA
GCACGCCGCCGAGTTGTTCGGTGTGGCGCAGTCGAGCATTTCCCGCTGGGAAAACGGCCGGCAAGCCATGGAACCGGCGG
AACGCGCGCGCTTGGAGCAACTGCTGGCGGCCAACCTCAGCGCCGCCGCCGACCAGGCCCTGGCGCGGCTGGTGCATGAC
AGCCCGCGCGCCGTGCACCTGGTGTGCGACCTGACCCACCGCCTGCTGGCCTGTTCCGTGACCCGCGCCGGGCAGTTCGG
CGTGCCCCTGAGCGAGCTGCTGGGGCAATCCCTGTGGGGCTTTTGCACCGAGGAAATCGTGCGCAAGGAAGCCGCCCTGG
ATGACCTGGGCTGGCGCGAAGTACTGGCCCCGCCGTCCCTGGAATTCTTCAGCGGCCACAACGATTCGGCCATCGTGCCC
ATCGCCCCCAGCCAGTGCCGCTGGACCCGCCTCAACCTCTCCGACGGCAACGCCGTGCGGCTGGTGGAAACCCTCTGA
ATGTCCGTAGCTCTGTTCACCTCACCCCATCTGGGCCTGGCCCTCAGGCGCTGGCGCCTGTTGCACCGGGTCAAGCAGCA
GCACGCCGCCGAGTTGTTCGGTGTGGCGCAGTCGAGCATTTCCCGCTGGGAAAACGGCCGGCAAGCCATGGAACCGGCGG
AACGCGCGCGCTTGGAGCAACTGCTGGCGGCCAACCTCAGCGCCGCCGCCGACCAGGCCCTGGCGCGGCTGGTGCATGAC
AGCCCGCGCGCCGTGCACCTGGTGTGCGACCTGACCCACCGCCTGCTGGCCTGTTCCGTGACCCGCGCCGGGCAGTTCGG
CGTGCCCCTGAGCGAGCTGCTGGGGCAATCCCTGTGGGGCTTTTGCACCGAGGAAATCGTGCGCAAGGAAGCCGCCCTGG
ATGACCTGGGCTGGCGCGAAGTACTGGCCCCGCCGTCCCTGGAATTCTTCAGCGGCCACAACGATTCGGCCATCGTGCCC
ATCGCCCCCAGCCAGTGCCGCTGGACCCGCCTCAACCTCTCCGACGGCAACGCCGTGCGGCTGGTGGAAACCCTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|