Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 179701..180217 Replicon chromosome
Accession NC_004129
Organism Pseudomonas protegens Pf-5

Toxin (Protein)


Gene name relE Uniprot ID F9XXF1
Locus tag PFL_RS00790 Protein ID WP_011058535.1
Coordinates 179936..180217 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q4KKD3
Locus tag PFL_RS00785 Protein ID WP_011058534.1
Coordinates 179701..179946 (+) Length 82 a.a.

Genomic Context

PFL_RS00770PFL_RS00775PFL_RS00780PFL_RS00785PFL_RS00790PFL_RS00795PFL_RS00800PFL_RS00805PFL_RS00810
Location: 177195..178805 (1611 bp)
Type: Others
Protein ID: WP_011058531.1
Location: 178915..179376 (462 bp)
Type: Others
Protein ID: WP_011058532.1
Location: 179391..179636 (246 bp)
Type: Others
Protein ID: WP_011058533.1
Location: 179701..179946 (246 bp)
Type: Antitoxin
Protein ID: WP_011058534.1
Location: 179936..180217 (282 bp)
Type: Toxin
Protein ID: WP_011058535.1
Location: 180360..180788 (429 bp)
Type: Others
Protein ID: WP_011058536.1
Location: 180785..182872 (2088 bp)
Type: Others
Protein ID: WP_011058537.1
Location: 182869..183078 (210 bp)
Type: Others
Protein ID: WP_011058538.1
Location: 183075..183965 (891 bp)
Type: Others
Protein ID: WP_011058539.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PFL_RS00770177195..178805+1611WP_011058531.1glycosyltransferase family 39 protein-
PFL_RS00775178915..179376+462WP_011058532.1YbaK/EbsC family protein-
PFL_RS00780179391..179636+246WP_011058533.1DUF2789 domain-containing protein-
PFL_RS00785179701..179946+246WP_011058534.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
PFL_RS00790179936..180217+282WP_011058535.1type II toxin-antitoxin system RelE/ParE family toxinToxin
PFL_RS00795180360..180788+429WP_011058536.1winged helix DNA-binding protein-
PFL_RS00800180785..182872+2088WP_011058537.1FUSC family protein-
PFL_RS00805182869..183078+210WP_011058538.1DUF1656 domain-containing protein-
PFL_RS00810183075..183965+891WP_011058539.1HlyD family secretion protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-69)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10839.72 Da        Isoelectric Point: 10.2298

>T20766 WP_011058535.1 NC_004129:179936-180217 [Pseudomonas protegens Pf-5]
MTYSLEFLPSAHKEWNKLGHTLREQFKKKLAERLEVPRIPADALHGLPDCYKIKLKASGYRLVYQVIEERVVVCVVAVGK
RERGTVYEQARKR

Download         Length: 282 bp

>T20766 NC_004129:179936-180217 [Pseudomonas protegens Pf-5]
ATGACTTATAGCCTTGAGTTCCTGCCTTCGGCACACAAGGAATGGAACAAGTTGGGGCATACGCTTCGAGAGCAATTCAA
GAAAAAGCTCGCCGAACGGCTTGAGGTGCCGCGAATCCCTGCTGATGCCCTGCATGGGCTTCCCGATTGCTACAAAATTA
AACTCAAGGCTTCGGGCTACCGATTGGTTTATCAAGTGATCGAAGAGCGCGTCGTGGTTTGCGTGGTTGCGGTCGGCAAG
CGCGAGCGTGGAACCGTTTACGAGCAGGCCAGGAAACGCTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8799.10 Da        Isoelectric Point: 4.3988

>AT20766 WP_011058534.1 NC_004129:179701-179946 [Pseudomonas protegens Pf-5]
MQSILADKAVSVSELKKNPSAVLSGAQGGPVAVLNHNRVMGYMVPAEVFEALMERLDDLELAEIIRERSHETPVPVSLDD
L

Download         Length: 246 bp

>AT20766 NC_004129:179701-179946 [Pseudomonas protegens Pf-5]
ATGCAGAGTATTCTGGCTGACAAAGCCGTCAGCGTATCTGAGTTGAAGAAAAACCCTTCTGCCGTCTTGAGTGGTGCCCA
GGGCGGGCCAGTGGCGGTGTTGAATCACAATCGTGTCATGGGCTACATGGTTCCGGCCGAGGTTTTCGAAGCGTTGATGG
AACGCCTGGATGATCTGGAGTTGGCCGAAATCATCCGCGAGCGCAGCCATGAGACGCCCGTTCCGGTCAGTCTGGATGAC
TTATAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBF9XXF1

Antitoxin

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Source
ID
Structure
AlphaFold DBQ4KKD3

References