Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4154794..4155313 Replicon chromosome
Accession NZ_CP077678
Organism Pseudomonas chlororaphis strain X8

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KS461_RS18800 Protein ID WP_162095625.1
Coordinates 4154794..4155075 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KS461_RS18805 Protein ID WP_162095626.1
Coordinates 4155065..4155313 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KS461_RS18775 (KS461_18695) 4150052..4150324 + 273 WP_162095623.1 hypothetical protein -
KS461_RS18780 (KS461_18700) 4151101..4151229 - 129 Protein_3711 ATP-binding protein -
KS461_RS18785 (KS461_18705) 4151320..4152111 + 792 WP_081360543.1 methyltransferase domain-containing protein -
KS461_RS18790 (KS461_18710) 4152427..4152909 + 483 WP_009049637.1 acyl-CoA thioesterase -
KS461_RS18795 (KS461_18715) 4152966..4154611 + 1646 Protein_3714 FMN-binding glutamate synthase family protein -
KS461_RS18800 (KS461_18720) 4154794..4155075 - 282 WP_162095625.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KS461_RS18805 (KS461_18725) 4155065..4155313 - 249 WP_162095626.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
KS461_RS18810 (KS461_18730) 4155401..4156189 - 789 WP_162095627.1 helix-turn-helix transcriptional regulator -
KS461_RS18815 (KS461_18735) 4156274..4157272 + 999 WP_081360539.1 bile acid:sodium symporter family protein -
KS461_RS18820 (KS461_18740) 4157487..4159250 + 1764 WP_202338431.1 hypothetical protein -
KS461_RS18825 (KS461_18745) 4159323..4159784 + 462 WP_009049642.1 YccF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10849.64 Da        Isoelectric Point: 10.6282

>T207449 WP_162095625.1 NZ_CP077678:c4155075-4154794 [Pseudomonas chlororaphis]
MTYELEFSEKAWREWQKLGPTLKEQFKKKLQERLVNPHVPADRLSGLGNAYKIKLRTAGYRLVYRVVDEVLVVTVIAVGK
RERGSVYQQASKR

Download         Length: 282 bp

>T207449 NZ_CP103108:859255-859515 [Parabacteroides faecis]
ATGGGGACAAAAGATAAATTGATAGATCGTTTTTGTAAGTTACCAAAAGATTTTACTTACGATGAAACTGTAAAGCTATT
GTCTGGGTTTGGCTATAATGTTCATAACAAAGGTGTTACTTCTGGTTCTCGTATTCGATTTAAGAATGATCAAACCGGAC
AGTATATAGATATCCACAAGCCTCATCCCGGAAGTATAATGAAAGAGTGGATGATGAAGTCTATTTATCAGCATTTAAAG
AGTAATGGTTTTATTAAATAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8996.43 Da        Isoelectric Point: 4.7512

>AT207449 WP_162095626.1 NZ_CP077678:c4155313-4155065 [Pseudomonas chlororaphis]
MTHVLLSNVVASISELKKNPMGTVAAGGGSSVAILNRNEPAFYCVPAKEYEAMMERLEDMELLALCRERKNDPTIKVSLD
DL

Download         Length: 249 bp

>AT207449 NZ_CP103108:859523-859864 [Parabacteroides faecis]
ATGGATTGTTTAGAATATAAAGGATATAAAGGAAGCGTTGAATATAGTAAAGCTGACAACTGTCTTTTTGGAAAAGTACT
TGGTATGAGTAAGGATCTTATTCTTTATGAAGGAAGTACCATTGATGAACTTCGCGCTGATTTCGAAGCTGGTATAGATA
GCTATATTGCAGGTTGCGAAGCAGATGGCGTTGAACCTCGCAAACCTTATAGCGGAACTTTGAATATCCGTATTTCTCCG
GAAGTTCATAGCCGTATTGCTATGTTGGCTCAGGAAGCTGGGATTACTATTAATGGATATATAAAAAATGCATTGGAGAA
CCAATTGAAAATGGCTCATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References