Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 323079..323749 Replicon chromosome
Accession NZ_CP077678
Organism Pseudomonas chlororaphis strain X8

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag KS461_RS01430 Protein ID WP_081362979.1
Coordinates 323079..323507 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag KS461_RS01435 Protein ID WP_162094241.1
Coordinates 323504..323749 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KS461_RS01415 (KS461_01415) 318198..320456 + 2259 WP_258256262.1 TonB-dependent receptor -
KS461_RS01420 (KS461_01420) 320503..321828 + 1326 WP_258256266.1 LLM class flavin-dependent oxidoreductase -
KS461_RS01425 (KS461_01425) 321913..322950 + 1038 WP_258256268.1 L-glyceraldehyde 3-phosphate reductase -
KS461_RS01430 (KS461_01430) 323079..323507 - 429 WP_081362979.1 type II toxin-antitoxin system VapC family toxin Toxin
KS461_RS01435 (KS461_01435) 323504..323749 - 246 WP_162094241.1 plasmid stabilization protein Antitoxin
KS461_RS01440 (KS461_01440) 323889..324728 - 840 WP_258256270.1 taurine dioxygenase -
KS461_RS01445 (KS461_01445) 324966..325805 - 840 WP_009046455.1 taurine ABC transporter permease TauC -
KS461_RS01450 (KS461_01450) 325802..326596 - 795 WP_124298266.1 taurine ABC transporter ATP-binding subunit -
KS461_RS01455 (KS461_01455) 326692..327669 - 978 WP_258256271.1 taurine ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15853.36 Da        Isoelectric Point: 5.4927

>T207445 WP_081362979.1 NZ_CP077678:c323507-323079 [Pseudomonas chlororaphis]
MIVLDTNVLSELMRPQPDTAVLLWIEAQPVEDLYISAMTMAEILHGIARLPHGKRKQTLHASAVAMFEEDFIDRIVPFGT
QAALYYAHLVSHRERSGQPINLVDAQIAAICRVHDAAIATRNTKDFTDTGLIVINPWLPLEV

Download         Length: 429 bp

>T207445 NZ_CP103066:c2219600-2219424 [Bacillus subtilis]
GTGCTTGAGAAAATGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9128.41 Da        Isoelectric Point: 7.3226

>AT207445 WP_162094241.1 NZ_CP077678:c323749-323504 [Pseudomonas chlororaphis]
MASLTIRNLDDHIKERLRIKAAHNGHSMEEEARLILRRALIRTADSQGLGSRIRARFAETGGVELELPERTEPARLVDLG
E

Download         Length: 246 bp

>AT207445 NZ_CP103066:2219541-2219641 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References