Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2173478..2173646 Replicon chromosome
Accession NZ_CP077673
Organism Klebsiella sp. PL-2018

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2173536..2173639 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2173478..2173646 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MKleb_RS10070 (MKleb_1954) 2168605..2170665 + 2061 WP_033836507.1 oligopeptidase B -
MKleb_RS10075 (MKleb_1955) 2170672..2171331 - 660 WP_014229839.1 exodeoxyribonuclease X -
MKleb_RS10080 (MKleb_1956) 2171410..2171640 - 231 WP_004103351.1 DNA polymerase III subunit theta -
MKleb_RS10085 (MKleb_1957) 2171776..2172150 + 375 WP_014229838.1 CopC domain-containing protein YobA -
MKleb_RS10090 (MKleb_1958) 2172155..2173024 + 870 WP_025106130.1 copper homeostasis membrane protein CopD -
MKleb_RS10095 (MKleb_1959) 2173041..2173379 + 339 WP_217076632.1 YebY family protein -
- 2173478..2173646 - 169 - - Antitoxin
- 2173536..2173639 + 104 - - Toxin
MKleb_RS10100 (MKleb_1960) 2173764..2174723 - 960 WP_025106131.1 spore coat protein U domain-containing protein -
MKleb_RS10105 (MKleb_1961) 2174738..2177068 - 2331 WP_025106132.1 fimbria/pilus outer membrane usher protein -
MKleb_RS10110 (MKleb_1962) 2177071..2177835 - 765 WP_025106133.1 fimbria/pilus periplasmic chaperone -
MKleb_RS10115 (MKleb_1963) 2177854..2178372 - 519 WP_004852079.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T207428 NZ_CP077673:2173536-2173639 [Klebsiella sp. PL-2018]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT207428 NZ_CP077673:c2173646-2173478 [Klebsiella sp. PL-2018]
AACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGCGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References