Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2019296..2019499 Replicon chromosome
Accession NZ_CP077660
Organism Enterobacter cloacae complex sp. ECL78

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2019389..2019492 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2019296..2019499 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KQQ04_RS09435 2015833..2016495 - 663 WP_015570288.1 exodeoxyribonuclease X -
KQQ04_RS09440 2016520..2017170 - 651 WP_003859783.1 carbon-nitrogen hydrolase family protein -
KQQ04_RS09445 2017282..2017512 - 231 WP_003859784.1 DNA polymerase III subunit theta -
KQQ04_RS09450 2017650..2018021 + 372 WP_022651439.1 CopC domain-containing protein YobA -
KQQ04_RS09455 2018023..2018892 + 870 WP_022651438.1 copper homeostasis membrane protein CopD -
KQQ04_RS09460 2018909..2019247 + 339 WP_003859787.1 YebY family protein -
- 2019296..2019499 - 204 - - Antitoxin
- 2019389..2019492 + 104 - - Toxin
KQQ04_RS09465 2019570..2020655 - 1086 WP_049125640.1 phage integrase Arm DNA-binding domain-containing protein -
KQQ04_RS09470 2020624..2020896 - 273 WP_023300430.1 excisionase -
KQQ04_RS09475 2021017..2021538 - 522 WP_049125635.1 hypothetical protein -
KQQ04_RS09480 2021595..2021810 - 216 WP_059356783.1 TraR/DksA family transcriptional regulator -
KQQ04_RS09485 2021813..2022115 - 303 WP_049126688.1 hypothetical protein -
KQQ04_RS09490 2022207..2022398 - 192 WP_049126690.1 DUF1382 family protein -
KQQ04_RS09495 2022395..2022712 - 318 WP_063927049.1 hypothetical protein -
KQQ04_RS09500 2022709..2022927 - 219 WP_126517466.1 hypothetical protein -
KQQ04_RS09505 2022924..2023475 - 552 WP_022651070.1 phage N-6-adenine-methyltransferase -
KQQ04_RS09510 2023472..2023624 - 153 WP_022651071.1 DUF1317 family protein -
KQQ04_RS09515 2023621..2024049 - 429 WP_022651072.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T207325 NZ_CP077660:2019389-2019492 [Enterobacter cloacae complex sp. ECL78]
GGCAAGGCGATTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 204 bp

>AT207325 NZ_CP077660:c2019499-2019296 [Enterobacter cloacae complex sp. ECL78]
AATAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTCAATCGCCTTGCCCTTTAAGAATAGATGACGACGTCAGGTTTTCCAGTCCACAGTAAAAGTG
GTCTGAAAAAAAGCGTCAGAACATCACTAAATGTGAAAAACCGC

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References